| Unique identifier for interactor A | uniprotkb:P0DPI0 |
| Unique identifier for interactor B | uniprotkb:Q9Z2I6 |
| Alternative identifier for interactor A | intact:EBI-8178893 uniprotkb:P18639 intact:MINT-1795451 uniprotkb:P01561 uniprotkb:A5HZZ9 uniprotkb:A7G1U9 uniprotkb:P10845 |
| Alternative identifier for interactor B | intact:EBI-8178859 intact:MINT-1795475 ensembl:ENSRNOP00000024459.3 |
| Aliases for A | psi-mi:bxa1_clobo(display_long) uniprotkb:botA(gene name) psi-mi:botA(display_short) uniprotkb:atx(gene name synonym) uniprotkb:Bontoxilysin-A(gene name synonym) uniprotkb:Botulinum neurotoxin type A1(gene name synonym) uniprotkb:bonT(gene name synonym) |
| Aliases for B | psi-mi:sv2c_rat(display_long) uniprotkb:Sv2c(gene name) psi-mi:Sv2c(display_short) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | - (2014) |
| Identifier of the publication | imex:IM-22230 pubmed:24583011 |
| NCBI Taxonomy identifier for interactor A | taxid:1491(clobo) taxid:1491(Clostridium botulinum) |
| NCBI Taxonomy identifier for interactor B | taxid:10116(rat) taxid:10116("Rattus norvegicus (Rat)") |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-9118895 imex:IM-22230-3 |
| Confidence score | intact-miscore:0.62 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f2 comment:"\"This direct protein-protein interaction is clearly demonstrated in a GST pull down assay employing full-length recombinant H6tBoNTA and rat GST-rSV2C 454-579 (Fig. 1A). The weaker binding of HCA to recombinant rat GST-rSV2A 468-594 is also shown (Fig. S1) whereas binding to non-glycosylated rSV2B is hardly detectable. Well characterised neutralising monoclonal antibodies directed against different epitopes within the HC-fragment of BoNT/A [25-29] were screened for interference with the SV2C interaction\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2014/02/06 |
| Update date | 2024/11/14 |
| negative Boolean value | false |
| Feature(s) for interactor A | mutation decreasing interaction:1131-1131 his tag:?-? |
| Feature(s) for interactor B | binding-associated region:454-579 glutathione s tranferase tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |