Curation Details
Interaction ID: MINT-8005353

Unique identifier for interactor Auniprotkb:O43524
Unique identifier for interactor Buniprotkb:P31749
Alternative identifier for interactor Aintact:EBI-1644164
uniprotkb:B4DVZ6
uniprotkb:Q9BZ04
uniprotkb:O15171
uniprotkb:Q5T2I7
uniprotkb:E1P5E6
Alternative identifier for interactor Bintact:EBI-296087
dip:DIP-24269N
uniprotkb:B7Z5R1
uniprotkb:B2RAM5
uniprotkb:Q9BWB6
Aliases for Apsi-mi:foxo3_human(display_long)
uniprotkb:FOXO3(gene name)
psi-mi:FOXO3(display_short)
uniprotkb:FKHRL1(gene name synonym)
uniprotkb:FOXO3A(gene name synonym)
uniprotkb:Forkhead in rhabdomyosarcoma-like 1(gene name synonym)
uniprotkb:AF6q21 protein(gene name synonym)
Aliases for Bpsi-mi:akt1_human(display_long)
uniprotkb:AKT1(gene name)
psi-mi:AKT1(display_short)
uniprotkb:PKB(gene name synonym)
uniprotkb:RAC(gene name synonym)
uniprotkb:RAC-PK-alpha(gene name synonym)
uniprotkb:Protein kinase B(gene name synonym)
uniprotkb:Proto-oncogene c-Akt(gene name synonym)
uniprotkb:Protein kinase B alpha(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorBrunet et al. (1999)
Identifier of the publicationpubmed:10102273
mint:MINT-5211323
imex:IM-27311
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-6970438
mint:MINT-8005353
imex:IM-27311-3
Confidence scoreintact-miscore:0.71
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role AUnspecified role
Experimental role BUnspecified role
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 1
causality statement:"\"P31749 (GO:0004672) decreases activity of O43524 (GO:0001228)\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2003/01/20
Update date2017/06/08
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?
mutation with no effect:315-315
mutation decreasing interaction rate:32-32
mutation decreasing interaction rate:253-253
Feature(s) for interactor Bha tag:?-?
mutation decreasing interaction rate:179-179
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant