Curation Details
Interaction ID: MINT-6380995

Unique identifier for interactor Auniprotkb:P01344
Unique identifier for interactor Buniprotkb:P11717
Alternative identifier for interactor Aintact:EBI-7178764
uniprotkb:E3UN45
uniprotkb:Q14299
intact:MINT-6380943
uniprotkb:B7WP08
uniprotkb:Q9UC69
uniprotkb:Q1WM26
uniprotkb:Q9UC68
uniprotkb:B3KX48
uniprotkb:P78449
uniprotkb:C9JAF2
ensembl:ENSP00000370796.1
ensembl:ENSP00000370802.1
ensembl:ENSP00000402047.2
ensembl:ENSP00000414497.2
Alternative identifier for interactor Bintact:EBI-1048580
uniprotkb:Q7Z7G9
uniprotkb:Q96PT5
ensembl:ENSP00000349437.1
Aliases for Apsi-mi:igf2_human(display_long)
uniprotkb:T3M-11-derived growth factor(gene name synonym)
uniprotkb:PP1446(orf name)
uniprotkb:IGF2(gene name)
psi-mi:IGF2(display_short)
uniprotkb:Somatomedin-A(gene name synonym)
Aliases for Bpsi-mi:mpri_human(display_long)
uniprotkb:Insulin-like growth factor 2 receptor(gene name synonym)
uniprotkb:Insulin-like growth factor II receptor(gene name synonym)
uniprotkb:M6P/IGF2 receptor(gene name synonym)
uniprotkb:300 kDa mannose 6-phosphate receptor(gene name synonym)
uniprotkb:IGF2R(gene name)
psi-mi:IGF2R(display_short)
uniprotkb:MPRI(gene name synonym)
Interaction detection methodspsi-mi:"MI:0107"(surface plasmon resonance)
First authorBrown et al. (2008)
Identifier of the publicationpubmed:18046459
imex:IM-11533
mint:MINT-6380932
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7706171
mint:MINT-6380995
imex:IM-11533-2
Confidence scoreintact-miscore:0.56
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F4 T2
comment:"\"KA(affinity constant)= 2.49 x 10^8/M The IGF2R-Dom10 13, IGF2R-Dom11 13 and IGF2R-Dom11 14 fragments were coupled directly to a biosensor surface via amine groups to give a final resonance value of 2000 U.\""
comment:homomint
comment:mint
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2008/02/20
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bbinding-associated region:?-?(MINT-6381000)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant