Curation Details
Interaction ID: IM-28915-5

Unique identifier for interactor Auniprotkb:A0A087WZ13
Unique identifier for interactor Buniprotkb:Q86TJ2
Alternative identifier for interactor Aintact:EBI-21272173
Alternative identifier for interactor Bintact:EBI-2512219
Aliases for Apsi-mi:a0a087wz13_human(display_long)
uniprotkb:RAVER1(gene name)
Aliases for Bpsi-mi:tad2b_human(display_long)
uniprotkb:TADA2B(gene name)
uniprotkb:ADA2B(gene name synonym)
uniprotkb:ADA2-like protein beta(gene name synonym)
Interaction detection methodspsi-mi:"MI:1314"(proximity-dependent biotin identification)
First authorVélot et al. (2021)
Identifier of the publicationimex:IM-28915
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:2364"(proximity)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26966033
Confidence scoreintact-miscore:0.27
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:"\"Only high-confidence interactions (SAINT score ≤0.9) were considered for follow-up experiments and analyses (supplemental Fig. 1A). We identified 31 proteins associated with AR in the absence of agonist (Fig. 2, supplemental Table S1). Strikingly, we also found that 182 and 200 (261 nonredundant) proteins were associated with AR upon stimulation with DHT for 24h or 72h, respectively\""
figure legend:ST1
comment:"\"Cells were treated with DHT (10 nM) for 72 h\""
agonist:"\"17β-hydroxy-5α-androstan-3-one (CHEBI:16330)\""
dataset:Cancer - Interactions investigated in the context of cancer
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-lapc4)
taxid:9606(Homo sapiens LAPC4 prostate carcinoma cell)
Parameters of the interaction-
Creation date2021/04/27
Update date2023/12/05
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ASequence tag identification
Participant identification method for interactor BSequence tag identification