Curation Details
Interaction ID: IM-28889-19

Unique identifier for interactor Auniprotkb:Q99608
Unique identifier for interactor Buniprotkb:P04406
Alternative identifier for interactor Aintact:EBI-718177
Alternative identifier for interactor Bintact:EBI-354056
Aliases for Apsi-mi:necd_human(display_long)
uniprotkb:NDN(gene name)
Aliases for Bpsi-mi:g3p_human(display_long)
uniprotkb:GAPDH(gene name)
uniprotkb:OK/SW-cl.12(orf name)
uniprotkb:CDABP0047(orf name)
uniprotkb:GAPD(gene name synonym)
uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)
Interaction detection methodspsi-mi:"MI:1314"(proximity-dependent biotin identification)
First authorSanderson et al. (2020)
Identifier of the publicationimex:IM-28889
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:2364"(proximity)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26957435
Confidence scoreintact-miscore:0.27
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST1 F6A F6B
comment:"\"We eliminated proteins found in only one of three replicate samples or present at high levels in a contaminant repository for affinity purification-mass spectrometry data (CRAPome Mellacheruvu et al. 2013). In all, 24 proteins were carried forward as necdin-proximate proteins.\""
comment:there is a large unexplained difference in interactor numbers between ST1 and Figure 6 results.
dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease
dataset:Brain Disease - Neurological Diseases & Disorders
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293flp-in)
taxid:9606(Homo sapiens HEK293flp-in embryonic kidney cell)
Parameters of the interaction-
Creation date2021/02/19
Update date2021/04/28
negative Boolean valuefalse
Feature(s) for interactor Afusion protein:c-c
flag tag:c-c
mutation with complex effect:280-280
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ASequence tag identification
Participant identification method for interactor BSequence tag identification