Curation Details
Interaction ID: IM-28889-11

Unique identifier for interactor Auniprotkb:Q99608
Unique identifier for interactor Buniprotkb:Q6P2Q9
Alternative identifier for interactor Aintact:EBI-718177
Alternative identifier for interactor Bintact:EBI-538479
Aliases for Apsi-mi:necd_human(display_long)
uniprotkb:NDN(gene name)
Aliases for Bpsi-mi:prp8_human(display_long)
uniprotkb:Splicing factor Prp8(gene name synonym)
uniprotkb:PRP8 homolog(gene name synonym)
uniprotkb:220 kDa U5 snRNP-specific protein(gene name synonym)
uniprotkb:p220(gene name synonym)
uniprotkb:PRPC8(gene name synonym)
uniprotkb:PRPF8(gene name)
Interaction detection methodspsi-mi:"MI:1314"(proximity-dependent biotin identification)
First authorSanderson et al. (2020)
Identifier of the publicationimex:IM-28889
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:2364"(proximity)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26955247
Confidence scoreintact-miscore:0.27
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:"\"Cells were treated with sodium arsenite (0.5 mM, 30 min) to induce stress granule formation.\""
comment:"\"After eliminating proteins found in only one of three replicate samples or present at high levels the CRAPome, 211 necdin-proximal proteins were identified in arsenite stressed cells (Suppl. Table 1).\""
figure legend:ST1
dataset:Brain Disease - Neurological Diseases & Disorders
dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293 flp-in)
taxid:9606(Homo sapiens)
Parameters of the interaction-
Creation date2021/02/19
Update date2022/06/23
negative Boolean valuefalse
Feature(s) for interactor Afusion protein:c-c
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor ASequence tag identification
Participant identification method for interactor BSequence tag identification