Curation Details
Interaction ID: IM-28561-1543

Unique identifier for interactor Auniprotkb:Q9BYB0
Unique identifier for interactor Buniprotkb:P21333
Alternative identifier for interactor Aintact:EBI-1752330
Alternative identifier for interactor Bintact:EBI-350432
Aliases for Apsi-mi:shan3_human(display_long)
uniprotkb:SHANK3(gene name)
uniprotkb:KIAA1650(gene name synonym)
uniprotkb:PSAP2(gene name synonym)
uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)
uniprotkb:PROSAP2(gene name synonym)
Aliases for Bpsi-mi:flna_human(display_long)
uniprotkb:FLNA(gene name)
uniprotkb:FLN(gene name synonym)
uniprotkb:FLN1(gene name synonym)
uniprotkb:Alpha-filamin(gene name synonym)
uniprotkb:Filamin-1(gene name synonym)
uniprotkb:Endothelial actin-binding protein(gene name synonym)
uniprotkb:Actin-binding protein 280(gene name synonym)
uniprotkb:Non-muscle filamin(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorSakai et al. (2011)
Identifier of the publicationdoi:10.1126/scitranslmed.3002166
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-26508619
Confidence scoreintact-miscore:0.51
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:SF1
dataset:"\"Autism - Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech and nonverbal communication.\""
dataset:Neurodevelopmental disease - Neurodevelopmental disorders are disabilities in the functioning of the brain that affect a child's behaviour, memory or ability to learn
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)
Parameters of the interaction-
Creation date2020/10/05
Update date2020/12/11
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?
sufficient binding region:1219-1731
Feature(s) for interactor Bmyc tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot