Unique identifier for interactor A | uniprotkb:Q86YC2 |
Unique identifier for interactor B | uniprotkb:Q06609 |
Alternative identifier for interactor A | intact:EBI-1222653 uniprotkb:Q8N7Y6 uniprotkb:Q8ND31 uniprotkb:Q9H6W1 uniprotkb:A6NIE1 ensembl:ENSP00000261584.4 |
Alternative identifier for interactor B | intact:EBI-297202 uniprotkb:Q6FHX9 uniprotkb:B0FXP0 uniprotkb:Q9BV60 intact:EBI-1059207 uniprotkb:B2R8T6 ensembl:ENSP00000267868.3 ensembl:ENSP00000433924.2 uniprotkb:Q6ZNA8 |
Aliases for A | psi-mi:palb2_human(display_long) uniprotkb:PALB2(gene name) psi-mi:PALB2(display_short) uniprotkb:FANCN(gene name synonym) |
Aliases for B | psi-mi:rad51_human(display_long) uniprotkb:RAD51(gene name) psi-mi:RAD51(display_short) uniprotkb:RAD51A(gene name synonym) uniprotkb:RECA(gene name synonym) uniprotkb:RAD51 homolog A(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
First author | Foo et al. (2017) |
Identifier of the publication | pubmed:28319063 imex:IM-26811 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0914"(association) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-21195816 imex:IM-26811-1 |
Confidence score | intact-miscore:0.80 |
Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Bait |
Experimental role B | Prey |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:fig 2c comment:"\"Y28C and L35P both abrogated the co-IP of the endogenous BRCA1 with the ectopically expressed PALB2 proteins in 293T cells, whereas K18R, K30N and R37H did not significantly affect the complex formation (Figure 2c and data not shown). Interactions of the PALB2 variants with BRCA2 and RAD51 were all unaffected, consistent with the fact that BRCA2 binds to the C terminus of PALB2.8\"" full coverage:Only protein-protein interactions curation depth:imex curation |
NCBI Taxonomy identifier for the host organism | taxid:9606(human-293t) taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) |
Parameters of the interaction | - |
Creation date | 2019/02/07 |
Update date | 2022/03/24 |
negative Boolean value | false |
Feature(s) for interactor A | tandem tag:c-c |
Feature(s) for interactor B | - |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Western blot |
Participant identification method for interactor B | Western blot |