| Unique identifier for interactor A | uniprotkb:Q96EB6 |
| Unique identifier for interactor B | uniprotkb:P37231 |
| Alternative identifier for interactor A | intact:EBI-1802965 uniprotkb:Q2XNF6 uniprotkb:Q5JVQ0 uniprotkb:Q9GZR9 uniprotkb:Q9Y6F0 ensembl:ENSP00000212015.6 |
| Alternative identifier for interactor B | intact:EBI-781384 uniprotkb:Q96J12 uniprotkb:O00684 uniprotkb:O00710 uniprotkb:O14515 uniprotkb:Q15178 uniprotkb:Q15179 uniprotkb:Q15180 uniprotkb:Q15832 uniprotkb:Q86U60 uniprotkb:A8K3G6 uniprotkb:B5BUA1 uniprotkb:Q0QJH8 ensembl:ENSP00000287820.6 |
| Aliases for A | psi-mi:sir1_human(display_long) uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym) uniprotkb:SIRT1(gene name) psi-mi:SIRT1(display_short) uniprotkb:SIR2L1(gene name synonym) uniprotkb:SIR2-like protein 1(gene name synonym) uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym) |
| Aliases for B | psi-mi:pparg_human(display_long) uniprotkb:Nuclear receptor subfamily 1 group C member 3(gene name synonym) uniprotkb:PPARG(gene name) psi-mi:PPARG(display_short) uniprotkb:NR1C3(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Han et al. (2010) |
| Identifier of the publication | pubmed:20660480 imex:IM-26767 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-20621748 imex:IM-26767-9 |
| Confidence score | intact-miscore:0.58 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:"\"Our results showed that the SIRT1 catalytic domain is required for PPARĪ³ to recruit SIRT1 ( Figure 3 B). Collectively, these data indicate that the SIRT1 catalytic domain is necessary and sufficient for the interaction of PPARĪ³ and SIRT1.\"" figure legend:f3b curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-hela) taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2018/07/11 |
| Update date | 2025/07/31 |
| negative Boolean value | false |
| Feature(s) for interactor A | myc tag:?-? necessary binding region:254-495 |
| Feature(s) for interactor B | flag tag:?-? |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |