Curation Details
Interaction ID: IM-26767-3

Unique identifier for interactor Aensembl:ENSG00000096717
Unique identifier for interactor Buniprotkb:Q96EB6
Alternative identifier for interactor Aintact:EBI-6267604
Alternative identifier for interactor Bintact:EBI-1802965
Aliases for Apsi-mi:sir1_human_gene(display_short)
Aliases for Bpsi-mi:sir1_human(display_long)
uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym)
uniprotkb:SIRT1(gene name)
uniprotkb:SIR2L1(gene name synonym)
uniprotkb:SIR2-like protein 1(gene name synonym)
uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0402"(chromatin immunoprecipitation assay)
First authorHan et al. (2010)
Identifier of the publicationpubmed:20660480
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-20621543
Confidence scoreintact-miscore:0.50
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AGene
Interactor type BProtein
Annotations for the interactionfigure legend:f4a
comment:"\"Indeed, the ChIP assay using SIRT1 antibody indicated that endogenous SIRT1 was present on its own promoter in HeLa cells ( Figure 4 A).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2018/07/11
Update date2018/07/11
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APrimer specific pcr
Participant identification method for interactor BPrimer specific pcr