Curation Details
Interaction ID: IM-24178-209

Unique identifier for interactor Auniprotkb:P05412
Unique identifier for interactor Buniprotkb:P12814
Alternative identifier for interactor Aintact:EBI-852823
Alternative identifier for interactor Bintact:EBI-351710
Aliases for Apsi-mi:jun_human(display_long)
uniprotkb:Transcription factor AP-1 subunit Jun(gene name synonym)
uniprotkb:JUN(gene name)
uniprotkb:Activator protein 1(gene name synonym)
uniprotkb:Proto-oncogene c-Jun(gene name synonym)
uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)
uniprotkb:p39(gene name synonym)
Aliases for Bpsi-mi:actn1_human(display_long)
uniprotkb:ACTN1(gene name)
uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)
uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)
uniprotkb:F-actin cross-linking protein(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorLi et al. (2015)
Identifier of the publicationimex:IM-24178
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-11323169
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:ST9
comment:"\"To confirm that these fraction‐specific complex formations truly reflect the endogenous situation, we further conducted endogenous JUN purifications in chromatin and soluble fractions (Supplementary Table S9). 65% high‐confident interactions identified by our tagged TAP/MS have been confirmed by these AP/MS using antibodies against endogenous JUN.\""
comment:Chromatin fraction
caution:[EBI-11323186] The protein has been merged with EBI-2656305 so the duplicated interactor has been deleted from this interaction.
caution:[EBI-11323208] The protein has been merged with EBI-2806743 so the duplicated interactor has been deleted from this interaction.
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens HEK293T embryonic kidney cell)
Parameters of the interaction-
Creation date2015/02/26
Update date2024/01/27
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BIdentification by mass spectrometry