Curation Details
Interaction ID: IM-24069-1

Unique identifier for interactor Auniprotkb:Q96CJ1
Unique identifier for interactor Buniprotkb:Q16665
Alternative identifier for interactor Aintact:EBI-1245604
Alternative identifier for interactor Bintact:EBI-447269
Aliases for Apsi-mi:eaf2_human(display_long)
uniprotkb:EAF2(gene name)
uniprotkb:TRAITS(gene name synonym)
uniprotkb:BM-040(orf name)
uniprotkb:Testosterone-regulated apoptosis inducer and tumor suppressor protein(gene name synonym)
Aliases for Bpsi-mi:hif1a_human(display_long)
uniprotkb:ARNT-interacting protein(gene name synonym)
uniprotkb:Member of PAS protein 1(gene name synonym)
uniprotkb:Basic-helix-loop-helix-PAS protein MOP1(gene name synonym)
uniprotkb:HIF1A(gene name)
uniprotkb:MOP1(gene name synonym)
uniprotkb:BHLHE78(gene name synonym)
uniprotkb:PASD8(gene name synonym)
uniprotkb:PAS domain-containing protein 8(gene name synonym)
uniprotkb:Class E basic helix-loop-helix protein 78(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorChen et al. (2014)
Identifier of the publicationimex:IM-24069
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-10766814
Confidence scoreintact-miscore:0.52
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f2a f2d f2e
comment:"\"All domains of HIF-1 could bind to EAF2 with varied binding affinity (Fig. 2E1 to E3).\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293t)
taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)
Parameters of the interaction-
Creation date2015/04/20
Update date2015/04/20
negative Boolean valuefalse
Feature(s) for interactor Aha tag:?-?
necessary binding region:36-49
Feature(s) for interactor Bmyc tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot