Curation Details
Interaction ID: IM-21648-4

Unique identifier for interactor Auniprotkb:Q13950
Unique identifier for interactor Buniprotkb:Q13526
Alternative identifier for interactor Aintact:EBI-976402
Alternative identifier for interactor Bintact:EBI-714158
Aliases for Apsi-mi:runx2_human(display_long)
uniprotkb:Oncogene AML-3(gene name synonym)
uniprotkb:Polyomavirus enhancer-binding protein 2 alpha A subunit(gene name synonym)
uniprotkb:SL3-3 enhancer factor 1 alpha A subunit(gene name synonym)
uniprotkb:SL3/AKV core-binding factor alpha A subunit(gene name synonym)
uniprotkb:Osteoblast-specific transcription factor 2(gene name synonym)
uniprotkb:Core-binding factor subunit alpha-1(gene name synonym)
uniprotkb:Acute myeloid leukemia 3 protein(gene name synonym)
uniprotkb:RUNX2(gene name)
uniprotkb:AML3(gene name synonym)
uniprotkb:CBFA1(gene name synonym)
uniprotkb:OSF2(gene name synonym)
uniprotkb:PEBP2A(gene name synonym)
Aliases for Bpsi-mi:pin1_human(display_long)
uniprotkb:Rotamase Pin1(gene name synonym)
uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin1(gene name synonym)
uniprotkb:PIN1(gene name)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorLee et al. (2013)
Identifier of the publicationimex:IM-21648
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8771971
Confidence scoreintact-miscore:0.59
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f2d
comment:"\". Lysates of Runx2 transfected cells were incubated with or without calf intestinal alkaline phosphatase (CIP) and subjected to immunoprecipitation. Dephosphorylation of Runx2 abolished the binding between Runx2 and Pin1 (Fig. 2D). These results indicate that Pin1 interacts with Runx2 in Runx2 phosphorylation-dependent manner.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293a)
taxid:9606(Homo sapiens)
Parameters of the interaction-
Creation date2013/09/25
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Amyc tag:?-?
Feature(s) for interactor Bxpress tag:?-?
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BPredetermined participant