Curation Details
Interaction ID: MINT-8425842

Unique identifier for interactor Auniprotkb:P35813
Unique identifier for interactor Buniprotkb:P28482
Alternative identifier for interactor Aintact:EBI-989143
uniprotkb:O75551
uniprotkb:B5BU11
uniprotkb:J3KNM0
ensembl:ENSP00000378514.4
Alternative identifier for interactor Bintact:EBI-959949
uniprotkb:A8CZ64
ensembl:ENSP00000215832.7
ensembl:ENSP00000381803.3
Aliases for Apsi-mi:ppm1a_human(display_long)
uniprotkb:Protein phosphatase 2C isoform alpha(gene name synonym)
uniprotkb:PPM1A(gene name)
psi-mi:PPM1A(display_short)
uniprotkb:PPPM1A(gene name synonym)
uniprotkb:Protein phosphatase IA(gene name synonym)
Aliases for Bpsi-mi:mk01_human(display_long)
uniprotkb:MAPK1(gene name)
psi-mi:MAPK1(display_short)
uniprotkb:ERK2(gene name synonym)
uniprotkb:PRKM1(gene name synonym)
uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)
uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)
uniprotkb:MAP kinase isoform p42(gene name synonym)
uniprotkb:ERT1(gene name synonym)
uniprotkb:PRKM2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorLi et al. (2013)
Identifier of the publicationmint:MINT-8425544
mint:fj-13-0002
pubmed:23560844
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8511194
mint:MINT-8425842
Confidence scoreintact-miscore:0.61
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:t3
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionkm:41.62x10^-6(molar)
Creation date2013/04/04
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor Atag:?-?(MINT-8425847)
mutation decreasing interaction:33-33(MINT-8425845)
Feature(s) for interactor Bhis tag:?-?(MINT-8425853)
binding-associated region:198-208(MINT-8425857)
phosphorylated residue:204-204(MINT-8425851)
phosphorylated residue:202-202(MINT-8425855)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPeptide synthesis