Curation Details
Interaction ID: MINT-8425720

Unique identifier for interactor Auniprotkb:P28482
Unique identifier for interactor Buniprotkb:P35813
Alternative identifier for interactor Aintact:EBI-959949
uniprotkb:A8CZ64
ensembl:ENSP00000215832.7
ensembl:ENSP00000381803.3
Alternative identifier for interactor Bintact:EBI-989143
uniprotkb:B5BU11
uniprotkb:J3KNM0
ensembl:ENSP00000378514.4
uniprotkb:O75551
Aliases for Apsi-mi:mk01_human(display_long)
uniprotkb:MAPK1(gene name)
psi-mi:MAPK1(display_short)
uniprotkb:ERK2(gene name synonym)
uniprotkb:PRKM1(gene name synonym)
uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)
uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)
uniprotkb:MAP kinase isoform p42(gene name synonym)
uniprotkb:ERT1(gene name synonym)
uniprotkb:PRKM2(gene name synonym)
Aliases for Bpsi-mi:ppm1a_human(display_long)
uniprotkb:Protein phosphatase 2C isoform alpha(gene name synonym)
uniprotkb:PPM1A(gene name)
psi-mi:PPM1A(display_short)
uniprotkb:PPPM1A(gene name synonym)
uniprotkb:Protein phosphatase IA(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorLi et al. (2013)
Identifier of the publicationmint:MINT-8425544
mint:fj-13-0002
pubmed:23560844
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8511126
mint:MINT-8425720
Confidence scoreintact-miscore:0.61
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:t2
comment:homomint
comment:mint
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionkm:16.25x10^-6(molar)
Creation date2013/04/04
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Amutation decreasing interaction:203-203(MINT-8425730)
phosphorylated residue:204-204(MINT-8425740)
his tag:?-?(MINT-8425728)
phosphorylated residue:202-202(MINT-8425726)
binding-associated region:198-208(MINT-8425724)
Feature(s) for interactor Btag:?-?(MINT-8425734)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APeptide synthesis
Participant identification method for interactor BPredetermined participant