| Unique identifier for interactor A | uniprotkb:P21359 |
| Unique identifier for interactor B | uniprotkb:Q14204 |
| Alternative identifier for interactor A | intact:EBI-1172917 uniprotkb:O00662 uniprotkb:Q14284 uniprotkb:Q14930 uniprotkb:Q9UMK3 uniprotkb:Q14931 ensembl:ENSP00000351015.4 |
| Alternative identifier for interactor B | intact:EBI-356015 intact:EBI-4399546 uniprotkb:Q6DKQ7 uniprotkb:Q8WU28 uniprotkb:Q92814 uniprotkb:Q9Y4G5 uniprotkb:B0I1R0 intact:EBI-28969816 ensembl:ENSP00000348965.4 |
| Aliases for A | psi-mi:nf1_human(display_long) uniprotkb:NF1(gene name) psi-mi:NF1(display_short) uniprotkb:Neurofibromatosis-related protein NF-1(gene name synonym) |
| Aliases for B | psi-mi:dyhc1_human(display_long) uniprotkb:DYNC1H1(gene name) psi-mi:DYNC1H1(display_short) uniprotkb:DNECL(gene name synonym) uniprotkb:KIAA0325(gene name synonym) uniprotkb:DNCH1(gene name synonym) uniprotkb:DNCL(gene name synonym) uniprotkb:DHC1(gene name synonym) uniprotkb:DYHC(gene name synonym) uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym) uniprotkb:Dynein heavy chain, cytosolic(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
| First author | Arun et al. (2013) |
| Identifier of the publication | mint:MINT-8416976 mint:d-13-00294r1 pubmed:23583712 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0915"(physical association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8513895 mint:MINT-8416984 |
| Confidence score | intact-miscore:0.40 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:homomint comment:mint figure legend:nf comment:"\"This interaction was further validation using the in situ Proximity Ligation Assay (PLA). \\"For the first time we demonstrate an interaction between NF1 and DHC in melanocytes. Using a combination of techniques such as PLA combined with immunofluorescence, we showed that this interaction occurred along MTs and colocalized with melanosomes\\"\"" |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-melanocyte) taxid:9606(Homo sapiens melanocyte) |
| Parameters of the interaction | - |
| Creation date | 2013/03/25 |
| Update date | 2024/11/29 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Identification by mass spectrometry |