Curation Details
Interaction ID: MINT-8412949

Unique identifier for interactor Auniprotkb:P51955
Unique identifier for interactor Buniprotkb:Q9UJX5
Alternative identifier for interactor Aintact:EBI-633182
ensembl:ENSP00000355966.4
uniprotkb:Q53FD6
uniprotkb:Q5VXZ1
intact:EBI-4311380
uniprotkb:Q5I1Z9
uniprotkb:Q6NZX8
uniprotkb:Q7Z634
uniprotkb:Q86XH2
uniprotkb:Q96QN9
Alternative identifier for interactor Bintact:EBI-2554854
uniprotkb:Q6PCC6
uniprotkb:A8K8H1
uniprotkb:Q9NSH6
intact:EBI-28973066
uniprotkb:E9PCR4
ensembl:ENSP00000318775.3
Aliases for Apsi-mi:nek2_human(display_long)
uniprotkb:NEK2A(gene name synonym)
uniprotkb:NimA-like protein kinase 1(gene name synonym)
uniprotkb:HSPK 21(gene name synonym)
uniprotkb:NEK2(gene name)
psi-mi:NEK2(display_short)
uniprotkb:NLK1(gene name synonym)
uniprotkb:Never in mitosis A-related kinase 2(gene name synonym)
Aliases for Bpsi-mi:apc4_human(display_long)
uniprotkb:APC4(gene name synonym)
uniprotkb:Cyclosome subunit 4(gene name synonym)
uniprotkb:ANAPC4(gene name)
psi-mi:ANAPC4(display_short)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorSedgwick et al. (2013)
Identifier of the publicationpubmed:23288039
imex:IM-18757
mint:MINT-8412929
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8292408
mint:MINT-8412949
imex:IM-18757-4
Confidence scoreintact-miscore:0.50
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:f5a f5b f5c f5d f5e
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2013/01/29
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Amutation decreasing interaction:320-320(MINT-8412990)
binding-associated region:301-333(MINT-8412979)
tandem tag:?-?(MINT-8412977)
mutation decreasing interaction:313-313(MINT-8412987)
mutation decreasing interaction:325-340(MINT-8412982)
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BPredetermined participant