Curation Details
Interaction ID: MINT-8412403

Unique identifier for interactor Auniprotkb:Q02750
Unique identifier for interactor Buniprotkb:P28482
Alternative identifier for interactor Aintact:EBI-492564
ensembl:ENSP00000302486.5
Alternative identifier for interactor Bintact:EBI-959949
uniprotkb:A8CZ64
ensembl:ENSP00000215832.7
ensembl:ENSP00000381803.3
Aliases for Apsi-mi:mp2k1_human(display_long)
uniprotkb:ERK activator kinase 1(gene name synonym)
uniprotkb:MAPK/ERK kinase 1(gene name synonym)
uniprotkb:MAP2K1(gene name)
psi-mi:MAP2K1(display_short)
uniprotkb:MEK1(gene name synonym)
uniprotkb:PRKMK1(gene name synonym)
Aliases for Bpsi-mi:mk01_human(display_long)
uniprotkb:MAPK1(gene name)
psi-mi:MAPK1(display_short)
uniprotkb:ERK2(gene name synonym)
uniprotkb:PRKM1(gene name synonym)
uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)
uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)
uniprotkb:MAP kinase isoform p42(gene name synonym)
uniprotkb:ERT1(gene name synonym)
uniprotkb:PRKM2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorVilleneuve et al. (2013)
Identifier of the publicationpubmed:23241949
imex:IM-18740
mint:MINT-8412360
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8279991
mint:MINT-8412403
imex:IM-18740-3
Confidence scoreintact-miscore:0.61
Complex expansion-
Biological role AEnzyme
Biological role BEnzyme target
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f9a
comment:homomint
comment:mint
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2013/01/28
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor Ahis tag:?-?(MINT-8412419)
mutation disrupting interaction:97-97(MINT-8412421)
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMolecular weight estimation by autoradiography
Participant identification method for interactor BMolecular weight estimation by autoradiography