Curation Details
Interaction ID: MINT-8398737

Unique identifier for interactor Auniprotkb:P35222
Unique identifier for interactor Buniprotkb:Q96AC1
Alternative identifier for interactor Aintact:EBI-491549
uniprotkb:Q8NEW9
uniprotkb:Q8NI94
uniprotkb:Q9H391
uniprotkb:A8K1L7
intact:EBI-491563
ensembl:ENSP00000344456.5
ensembl:ENSP00000379486.3
ensembl:ENSP00000379488.3
ensembl:ENSP00000385604.1
ensembl:ENSP00000387455.2
ensembl:ENSP00000401599.2
ensembl:ENSP00000409302.2
ensembl:ENSP00000412219.2
ensembl:ENSP00000493533.1
ensembl:ENSP00000493610.1
ensembl:ENSP00000494053.1
ensembl:ENSP00000494411.1
ensembl:ENSP00000494677.1
ensembl:ENSP00000494845.1
ensembl:ENSP00000494914.1
ensembl:ENSP00000495076.1
ensembl:ENSP00000495244.1
ensembl:ENSP00000495360.1
ensembl:ENSP00000495450.1
ensembl:ENSP00000495719.1
ensembl:ENSP00000495992.1
ensembl:ENSP00000496021.1
ensembl:ENSP00000496180.1
ensembl:ENSP00000496385.1
Alternative identifier for interactor Bintact:EBI-4399465
uniprotkb:Q14840
uniprotkb:Q86TY7
uniprotkb:B5TJY2
ensembl:ENSP00000340391.3
ensembl:ENSP00000378993.2
intact:EBI-21355423
Aliases for Apsi-mi:ctnb1_human(display_long)
uniprotkb:Beta-catenin(gene name synonym)
uniprotkb:OK/SW-cl.35(orf name)
uniprotkb:PRO2286(orf name)
uniprotkb:CTNNB1(gene name)
psi-mi:CTNNB1(display_short)
uniprotkb:CTNNB(gene name synonym)
Aliases for Bpsi-mi:ferm2_human(display_long)
uniprotkb:FERMT2(gene name)
psi-mi:FERMT2(display_short)
uniprotkb:KIND2(gene name synonym)
uniprotkb:MIG2(gene name synonym)
uniprotkb:PLEKHC1(gene name synonym)
uniprotkb:Kindlin-2(gene name synonym)
uniprotkb:Mitogen-inducible gene 2 protein(gene name synonym)
uniprotkb:Pleckstrin homology domain-containing family C member 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorYu et al. (2012)
Identifier of the publicationdoi:10.1038/embor.2012.88
pubmed:22699938
imex:IM-20820
mint:MINT-8398552
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7928198
mint:MINT-8398737
imex:IM-20820-7
Confidence scoreintact-miscore:0.68
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
comment:"\"The interaction between endogenous Kindlin 2 and b-catenin was identified by co-immunoprecipitation (Co-IP) in breast cancer cells ( MDA-MB-231, and Hs578T), non-cancer-derived cells (HEK293T), and normal cells (human proximal tubular epithelial HKC cells,supplementary Fig S2A D online).\""
figure legend:sf2a sf2b sf2c sf2d sf4a sf4b sf4c sf4d
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human)
taxid:9606(Homo sapiens)
Parameters of the interaction-
Creation date2012/10/12
Update date2024/11/28
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot