Unique identifier for interactor A | uniprotkb:O14757 |
Unique identifier for interactor B | uniprotkb:Q9UJM3 |
Alternative identifier for interactor A | intact:EBI-974488 uniprotkb:B4DDD0 uniprotkb:F5H7S4 uniprotkb:A8K934 uniprotkb:B4DSK3 uniprotkb:B5BTY6 uniprotkb:H2BI51 ensembl:ENSP00000388648.1 ensembl:ENSP00000412504.2 ensembl:ENSP00000432890.1 ensembl:ENSP00000435371.1 ensembl:ENSP00000481616.2 |
Alternative identifier for interactor B | intact:EBI-2941912 intact:EBI-28986605 uniprotkb:B2RDX9 uniprotkb:Q9NTG9 uniprotkb:Q9UD05 ensembl:ENSP00000366702.5 |
Aliases for A | psi-mi:chk1_human(display_long) uniprotkb:CHEK1(gene name) psi-mi:CHEK1(display_short) uniprotkb:CHK1(gene name synonym) uniprotkb:CHK1 checkpoint homolog(gene name synonym) uniprotkb:Checkpoint kinase-1(gene name synonym) uniprotkb:Cell cycle checkpoint kinase(gene name synonym) |
Aliases for B | psi-mi:errfi_human(display_long) uniprotkb:ERRFI1(gene name) psi-mi:ERRFI1(display_short) uniprotkb:MIG6(gene name synonym) uniprotkb:Mitogen-inducible gene 6 protein(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0415"(enzymatic study) |
First author | Liu et al. (2012) |
Identifier of the publication | doi:10.1038/emboj.2012.88 pubmed:22505024 imex:IM-18771 mint:MINT-8382427 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0217"(phosphorylation reaction) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-7820452 mint:MINT-8382456 imex:IM-18771-2 |
Confidence score | intact-miscore:0.44 |
Complex expansion | - |
Biological role A | Enzyme |
Biological role B | Enzyme target |
Experimental role A | Neutral component |
Experimental role B | Neutral component |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | comment:homomint comment:mint figure legend:f2a f3b sf3a sf4b curation depth:imex curation full coverage:Only protein-protein interactions |
NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
Parameters of the interaction | - |
Creation date | 2012/06/08 |
Update date | 2024/11/14 |
negative Boolean value | false |
Feature(s) for interactor A | glutathione s tranferase tag:?-?(MINT-8382465) |
Feature(s) for interactor B | mutation decreasing interaction:302-302(MINT-8382469) mutation decreasing interaction:251-251(MINT-8382461) mutation decreasing interaction:249-249(MINT-8382459) phosphorylated residue:251-251(MINT-8382487) mutation decreasing interaction:334-334(MINT-8382472) mutation decreasing interaction:369-369(MINT-8382475) |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Molecular weight estimation by autoradiography |
Participant identification method for interactor B | Molecular weight estimation by autoradiography |