Curation Details
Interaction ID: MINT-8362017

Unique identifier for interactor Auniprotkb:P62993
Unique identifier for interactor Buniprotkb:Q13480
Alternative identifier for interactor Aintact:EBI-401755
uniprotkb:P29354
uniprotkb:Q14450
uniprotkb:Q63057
uniprotkb:Q63059
ensembl:ENSP00000339007.4
ensembl:ENSP00000376345.1
ensembl:ENSP00000376347.1
ensembl:ENSP00000496913.1
Alternative identifier for interactor Bintact:EBI-517684
uniprotkb:Q4W5G2
uniprotkb:Q6P1W2
ensembl:ENSP00000262994.4
uniprotkb:A8K152
Aliases for Apsi-mi:grb2_human(display_long)
uniprotkb:GRB2(gene name)
psi-mi:GRB2(display_short)
uniprotkb:ASH(gene name synonym)
uniprotkb:Adapter protein GRB2(gene name synonym)
uniprotkb:SH2/SH3 adapter GRB2(gene name synonym)
uniprotkb:Protein Ash(gene name synonym)
Aliases for Bpsi-mi:gab1_human(display_long)
uniprotkb:Growth factor receptor bound protein 2-associated protein 1(gene name synonym)
uniprotkb:GRB2-associated binder 1(gene name synonym)
uniprotkb:GAB1(gene name)
psi-mi:GAB1(display_short)
Interaction detection methodspsi-mi:"MI:0065"(isothermal titration calorimetry)
First authorMcDonald et al. (2012)
Identifier of the publicationpubmed:22536782
mint:MINT-8361992
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7836848
mint:MINT-8362017
Confidence scoreintact-miscore:0.93
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:f4 t3
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionkd:20.26x10^-6(molar)
Creation date2012/04/12
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Ahis tag:?-?(MINT-8362026)
Feature(s) for interactor Bmutation decreasing interaction:521-521(MINT-8362032)
his tag:?-?(MINT-8362022)
mutation decreasing interaction:524-524(MINT-8362040)
mutation decreasing interaction:522-522(MINT-8362034)
binding-associated region:331-530(MINT-8362020)
mutation decreasing interaction:523-523(MINT-8362037)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant