Curation Details
Interaction ID: MINT-8329981

Unique identifier for interactor Auniprotkb:P35569
Unique identifier for interactor Buniprotkb:P08069
Alternative identifier for interactor Aintact:EBI-400825
Alternative identifier for interactor Bintact:EBI-475981
uniprotkb:Q14CV2
uniprotkb:B1B5Y2
uniprotkb:Q9UCC0
ensembl:ENSP00000497069.1
Aliases for Apsi-mi:irs1_mouse(display_long)
uniprotkb:Irs1(gene name)
psi-mi:Irs1(display_short)
uniprotkb:Irs-1(gene name synonym)
Aliases for Bpsi-mi:igf1r_human(display_long)
uniprotkb:Insulin-like growth factor I receptor(gene name synonym)
uniprotkb:IGF1R(gene name)
psi-mi:IGF1R(display_short)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorWarsito et al. (2012)
Identifier of the publicationpubmed:22261717
imex:IM-20826
mint:MINT-8329621
NCBI Taxonomy identifier for interactor Ataxid:10090(mouse)
taxid:10090(Mus musculus)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7654276
mint:MINT-8329981
imex:IM-20826-4
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f2d
comment:mint
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:10090(mouse-r-)
taxid:10090("Mouse R- cells (embryonic fibroblasts lacking type-1 IGF receptor)")
Parameters of the interaction-
Creation date2012/03/09
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bmutation disrupting interaction:950-950(MINT-8331075)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot