Curation Details
Interaction ID: MINT-8310762

Unique identifier for interactor Auniprotkb:P29350
Unique identifier for interactor Buniprotkb:P06239
Alternative identifier for interactor Aintact:EBI-78260
intact:EBI-28977917
uniprotkb:Q969V8
uniprotkb:A8K306
uniprotkb:G3V0F8
uniprotkb:Q9UK67
ensembl:ENSP00000326010.9
Alternative identifier for interactor Bintact:EBI-1348
uniprotkb:P07100
uniprotkb:Q12850
uniprotkb:Q13152
uniprotkb:Q5TDH8
uniprotkb:Q5TDH9
uniprotkb:Q96DW4
uniprotkb:Q9NYT8
ensembl:ENSP00000337825.5
uniprotkb:Q7RTZ3
uniprotkb:D3DPP8
Aliases for Apsi-mi:ptn6_human(display_long)
uniprotkb:PTPN6(gene name)
psi-mi:PTPN6(display_short)
uniprotkb:HCP(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)
uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)
uniprotkb:SH-PTP1(gene name synonym)
uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)
uniprotkb:PTP1C(gene name synonym)
Aliases for Bpsi-mi:lck_human(display_long)
uniprotkb:Protein YT16(gene name synonym)
uniprotkb:Proto-oncogene Lck(gene name synonym)
uniprotkb:T cell-specific protein-tyrosine kinase(gene name synonym)
uniprotkb:LCK(gene name)
psi-mi:LCK(display_short)
uniprotkb:Lymphocyte cell-specific protein-tyrosine kinase(gene name synonym)
uniprotkb:p56-LCK(gene name synonym)
uniprotkb:Leukocyte C-terminal Src kinase(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorLorenz et al. (1994)
Identifier of the publicationmint:MINT-7028063
pubmed:8114715
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8641092
mint:MINT-8310762
Confidence scoreintact-miscore:0.62
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role AUnspecified role
Experimental role BUnspecified role
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:F6 F7
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2012/02/13
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:530-542(MINT-8310766)
phosphorylated residue:536-536(MINT-8310771)
mutation decreasing interaction:536-536(MINT-8310768)
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant