| Unique identifier for interactor A | uniprotkb:Q15796 |
| Unique identifier for interactor B | uniprotkb:Q9HAU4 |
| Alternative identifier for interactor A | intact:EBI-1040141 ensembl:ENSP00000262160.6 ensembl:ENSP00000384449.1 |
| Alternative identifier for interactor B | intact:EBI-396727 ensembl:ENSP00000262435.9 uniprotkb:Q52LL1 uniprotkb:Q9H260 |
| Aliases for A | psi-mi:smad2_human(display_long) uniprotkb:SMAD2(gene name) psi-mi:SMAD2(display_short) uniprotkb:MADH2(gene name synonym) uniprotkb:MADR2(gene name synonym) uniprotkb:Mad-related protein 2(gene name synonym) uniprotkb:SMAD family member 2(gene name synonym) uniprotkb:JV18-1(gene name synonym) |
| Aliases for B | psi-mi:smuf2_human(display_long) uniprotkb:SMURF2(gene name) psi-mi:SMURF2(display_short) uniprotkb:SMAD ubiquitination regulatory factor 2(gene name synonym) uniprotkb:SMAD-specific E3 ubiquitin-protein ligase 2(gene name synonym) uniprotkb:HECT-type E3 ubiquitin transferase SMURF2(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0065"(isothermal titration calorimetry) |
| First author | Tang et al. (2011) |
| Identifier of the publication | doi:10.1038/emboj.2011.393 pubmed:22045334 imex:IM-16658 mint:MINT-8308197 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-7500811 mint:MINT-8308318 imex:IM-16658-7 |
| Confidence score | intact-miscore:0.81 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:homomint figure legend:Fig. 5c comment:domino comment:mint kinetic_conditions:Temp = 25C dataset:IBD - Inflammatory bowel disease full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | kd:255.0x10^-9 ~24.0(molar) |
| Creation date | 2012/02/07 |
| Update date | 2014/10/28 |
| negative Boolean value | false |
| Feature(s) for interactor A | sufficient binding region:214-230(MINT-8308327) O-phospho-L-threonine:220-220(MINT-8308329) |
| Feature(s) for interactor B | sufficient binding region:248-367(MINT-8308322) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Peptide synthesis |
| Participant identification method for interactor B | Predetermined participant |