Curation Details
Interaction ID: MINT-8308205

Unique identifier for interactor Auniprotkb:P84022
Unique identifier for interactor Buniprotkb:Q9HAU4
Alternative identifier for interactor Aintact:EBI-347161
intact:EBI-1760241
uniprotkb:O09064
uniprotkb:O09144
uniprotkb:O14510
uniprotkb:O35273
uniprotkb:Q92940
uniprotkb:Q93002
uniprotkb:Q9GKR4
intact:EBI-1965323
uniprotkb:A8K4B6
uniprotkb:B7Z9Q2
uniprotkb:B7Z4Z5
uniprotkb:B7Z6M9
uniprotkb:F5H383
ensembl:ENSP00000332973.4
Alternative identifier for interactor Bintact:EBI-396727
uniprotkb:Q52LL1
uniprotkb:Q9H260
ensembl:ENSP00000262435.9
Aliases for Apsi-mi:smad3_human(display_long)
uniprotkb:SMAD3(gene name)
psi-mi:SMAD3(display_short)
uniprotkb:MADH3(gene name synonym)
uniprotkb:SMAD family member 3(gene name synonym)
uniprotkb:JV15-2(gene name synonym)
Aliases for Bpsi-mi:smuf2_human(display_long)
uniprotkb:SMURF2(gene name)
psi-mi:SMURF2(display_short)
uniprotkb:SMAD ubiquitination regulatory factor 2(gene name synonym)
uniprotkb:SMAD-specific E3 ubiquitin-protein ligase 2(gene name synonym)
uniprotkb:HECT-type E3 ubiquitin transferase SMURF2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorTang et al. (2011)
Identifier of the publicationdoi:10.1038/emboj.2011.393
pubmed:22045334
imex:IM-16658
mint:MINT-8308197
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7500507
mint:MINT-8308205
imex:IM-16658-1
Confidence scoreintact-miscore:0.80
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:Fig. 5a
comment:homomint
comment:mint
curation depth:imex curation
full coverage:Only protein-protein interactions
dataset:IBD - Inflammatory bowel disease
NCBI Taxonomy identifier for the host organismtaxid:9606(human-293)
taxid:9606(Homo sapiens HEK293 embryonic kidney cell)
Parameters of the interaction-
Creation date2012/02/07
Update date2024/11/29
negative Boolean valuefalse
Feature(s) for interactor Amutation disrupting interaction:179-179(MINT-8308217)
mutation disrupting interaction:204-204,208-208,179-179,213-213(MINT-8308220)
flag tag:?-?(MINT-8308214)
Feature(s) for interactor Bmyc tag:?-?(MINT-8308210)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot