Curation Details
Interaction ID: MINT-8302498

Unique identifier for interactor Auniprotkb:Q8NBP7
Unique identifier for interactor Buniprotkb:P01130
Alternative identifier for interactor Aintact:EBI-7539251
ensembl:ENSP00000303208.5
intact:MINT-3041747
uniprotkb:C0JYY9
uniprotkb:Q5SZQ2
uniprotkb:Q5PSM5
intact:MINT-4888810
uniprotkb:A8T640
Alternative identifier for interactor Bintact:EBI-988319
uniprotkb:B4DJZ8
uniprotkb:C0JYY8
uniprotkb:Q9UDH7
uniprotkb:B4DR00
uniprotkb:B4DTQ3
uniprotkb:H0YLU8
uniprotkb:Q59FQ1
uniprotkb:B4DII3
uniprotkb:H0YNT7
ensembl:ENSP00000454071.1
uniprotkb:Q53ZD9
Aliases for Apsi-mi:pcsk9_human(display_long)
uniprotkb:Subtilisin/kexin-like protease PC9(gene name synonym)
uniprotkb:Neural apoptosis-regulated convertase 1(gene name synonym)
uniprotkb:Proprotein convertase 9(gene name synonym)
uniprotkb:PCSK9(gene name)
psi-mi:PCSK9(display_short)
uniprotkb:NARC1(gene name synonym)
uniprotkb:PSEC0052(orf name)
Aliases for Bpsi-mi:ldlr_human(display_long)
uniprotkb:LDLR(gene name)
psi-mi:LDLR(display_short)
Interaction detection methodspsi-mi:"MI:0107"(surface plasmon resonance)
First authorLo et al. (2011)
Identifier of the publicationpubmed:22081141
imex:IM-16526
mint:MINT-8298560
doi:10.1038/embor.2011.205
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7539553
mint:MINT-8302498
imex:IM-16526-5
Confidence scoreintact-miscore:0.68
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:sf3.5 t1
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interactionkd:2960.0x10^-9(molar)
Creation date2011/12/14
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bbinding-associated region:22-789(MINT-8302524)
mutation decreasing interaction:656-656(MINT-8302502)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant