| Unique identifier for interactor A | uniprotkb:O60235 |
| Unique identifier for interactor B | uniprotkb:P26927 |
| Alternative identifier for interactor A | intact:EBI-7639969 intact:MINT-8302106 uniprotkb:Q08AF6 ensembl:ENSP00000283916.6 |
| Alternative identifier for interactor B | intact:EBI-6929133 uniprotkb:Q6GTN4 uniprotkb:A8MSX3 uniprotkb:Q14870 uniprotkb:Q13350 uniprotkb:A6NLA3 |
| Aliases for A | psi-mi:tm11d_human(display_long) uniprotkb:TMPRSS11D(gene name) psi-mi:TMPRSS11D(display_short) uniprotkb:Airway trypsin-like protease(gene name synonym) uniprotkb:HAT(gene name synonym) |
| Aliases for B | psi-mi:hgfl_human(display_long) uniprotkb:D3F15S2(gene name synonym) uniprotkb:DNF15S2(gene name synonym) uniprotkb:HGFL(gene name synonym) uniprotkb:Macrophage stimulatory protein(gene name synonym) uniprotkb:Macrophage-stimulating protein(gene name synonym) uniprotkb:MST1(gene name) psi-mi:MST1(display_short) |
| Interaction detection methods | psi-mi:"MI:0435"(protease assay) |
| First author | Orikawa et al. (2012) |
| Identifier of the publication | pubmed:22245154 imex:IM-16811 mint:MINT-8302077 doi:10.1016/j.febslet.2012.01.009 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0194"(cleavage reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-7639963 mint:MINT-8302112 imex:IM-16811-1 |
| Confidence score | intact-miscore:0.44 |
| Complex expansion | - |
| Biological role A | Enzyme |
| Biological role B | Enzyme target |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:F1 comment:homomint comment:mint resulting-ptm:cleavage of P26927 at the arg483-val484 peptide bond causality statement:O60235 is required for cleavage of P26927 causality statement:O60235 increases activity of P26927 causality statement:O60235 increases quantity of PRO_0000028086 causality statement:O60235 increases quantity of PRO_0000028087 comment:"\"Processing of HGFL/MST (P26927) by TM11D/HAT (O60235) was suppressed at higher sodium chloride (NaCl) concentrations (tested at 50, 150 and 200 millimolar NaCl).\"" dataset:IBD - Inflammatory bowel disease full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2012/01/04 |
| Update date | 2014/10/24 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | uncategorized protein modification:483-484(MINT-8302126) his tag:c-c(MINT-8302116) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Edman degradation |