Curation Details
Interaction ID: MINT-8298439

Unique identifier for interactor Auniprotkb:Q9H469
Unique identifier for interactor Buniprotkb:Q9HAU4
Alternative identifier for interactor Aintact:EBI-6144096
uniprotkb:B1AKX9
uniprotkb:Q0D2Q3
uniprotkb:A1L4J8
uniprotkb:C9JWA4
uniprotkb:Q5JWA5
uniprotkb:Q49AL7
uniprotkb:B1AKY1
uniprotkb:B1AKY0
uniprotkb:B1AKX8
ensembl:ENSP00000358972.3
Alternative identifier for interactor Bintact:EBI-396727
ensembl:ENSP00000262435.9
uniprotkb:Q52LL1
uniprotkb:Q9H260
Aliases for Apsi-mi:fxl15_human(display_long)
uniprotkb:F-box only protein 37(gene name synonym)
uniprotkb:FBXO37(gene name synonym)
uniprotkb:FBXL15(gene name)
psi-mi:FBXL15(display_short)
Aliases for Bpsi-mi:smuf2_human(display_long)
uniprotkb:SMURF2(gene name)
psi-mi:SMURF2(display_short)
uniprotkb:SMAD ubiquitination regulatory factor 2(gene name synonym)
uniprotkb:SMAD-specific E3 ubiquitin-protein ligase 2(gene name synonym)
uniprotkb:HECT-type E3 ubiquitin transferase SMURF2(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorCui et al. (2011)
Identifier of the publicationpubmed:21572392
imex:IM-16338
mint:MINT-8198822
doi:10.1038/emboj.2011.155
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-6946076
mint:MINT-8298439
imex:IM-16338-6
Confidence scoreintact-miscore:0.60
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:sf6a
causality statement:Q9H469 is required for ubiquitination of Q9HAU4
causality statement:Q9H469 increases degradation at protein level of Q9HAU4
dataset:IBD - Inflammatory bowel disease
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2011/07/15
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?(MINT-8298447)
Feature(s) for interactor Bhis tag:?-?(MINT-8298443)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot