Curation Details
Interaction ID: MINT-8297217

Unique identifier for interactor Auniprotkb:P05771-2
Unique identifier for interactor Buniprotkb:O60346
Alternative identifier for interactor Aintact:EBI-5774511
intact:EBI-7750711
intact:MINT-241045
intact:EBI-7750580
intact:EBI-7750734
intact:EBI-7750836
intact:EBI-7750757
intact:EBI-7062973
intact:EBI-7063086
intact:EBI-7750664
intact:EBI-7750879
intact:EBI-7750925
ensembl:ENSP00000496129.1
Alternative identifier for interactor Bintact:EBI-2511516
uniprotkb:Q6PJI6
uniprotkb:Q6P4C4
uniprotkb:A1A4F5
uniprotkb:Q641Q7
uniprotkb:Q86TN6
uniprotkb:Q96FK2
uniprotkb:Q9NUY1
ensembl:ENSP00000262719.4
intact:EBI-28974360
Aliases for Apsi-mi:p05771-2(display_long)
uniprotkb:PKCB(gene name synonym)
uniprotkb:PRKCB1(gene name synonym)
uniprotkb:PRKCB2(isoform synonym)
uniprotkb:PRKCB(gene name)
psi-mi:PRKCB(display_short)
Aliases for Bpsi-mi:phlp1_human(display_long)
uniprotkb:PHLPP1(gene name)
psi-mi:PHLPP1(display_short)
uniprotkb:KIAA0606(gene name synonym)
uniprotkb:PHLPP(gene name synonym)
uniprotkb:PLEKHE1(gene name synonym)
uniprotkb:SCOP(gene name synonym)
uniprotkb:Pleckstrin homology domain-containing family E member 1(gene name synonym)
uniprotkb:Suprachiasmatic nucleus circadian oscillatory protein(gene name synonym)
Interaction detection methodspsi-mi:"MI:0434"(phosphatase assay)
First authorGao et al. (2008)
Identifier of the publicationdoi:10.1074/jbc.M707319200
pubmed:18162466
mint:MINT-8296472
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0203"(dephosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7750591
mint:MINT-8297217
Confidence scoreintact-miscore:0.60
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F1A
comment:mint
causality statement:O60346 is required for dephosphorylation of P05771-2
causality statement:O60346 increases degradation at protein level of P05771-2
dataset:IBD - Inflammatory bowel disease
partial coverage:partial coverage
curation depth:rapid curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2011/11/30
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Ahis tag:?-?
Feature(s) for interactor Bglutathione s tranferase tag:?-?
sufficient binding region:1165-1418(IPR001932)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot