Curation Details
Interaction ID: MINT-8258197

Unique identifier for interactor Auniprotkb:P35914
Unique identifier for interactor Buniprotkb:Q14469
Alternative identifier for interactor Aintact:EBI-721399
uniprotkb:B7UCC6
uniprotkb:D3Y5K7
uniprotkb:Q6IBC0
uniprotkb:Q96FP8
uniprotkb:B4DUP4
ensembl:ENSP00000363614.3
Alternative identifier for interactor Bintact:EBI-2832522
uniprotkb:Q6FHB2
ensembl:ENSP00000232424.3
Aliases for Apsi-mi:hmgcl_human(display_long)
uniprotkb:3-hydroxy-3-methylglutarate-CoA lyase(gene name synonym)
uniprotkb:HMGCL(gene name)
psi-mi:HMGCL(display_short)
Aliases for Bpsi-mi:hes1_human(display_long)
uniprotkb:HES1(gene name)
psi-mi:HES1(display_short)
uniprotkb:BHLHB39(gene name synonym)
uniprotkb:HL(gene name synonym)
uniprotkb:HRY(gene name synonym)
uniprotkb:Class B basic helix-loop-helix protein 39(gene name synonym)
uniprotkb:Hairy and enhancer of split 1(gene name synonym)
uniprotkb:Hairy homolog(gene name synonym)
uniprotkb:Hairy-like protein(gene name synonym)
Interaction detection methodspsi-mi:"MI:0018"(two hybrid)
First authorVinayagam et al. (2011)
Identifier of the publicationpubmed:21900206
imex:IM-16799
mint:MINT-8089645
doi:10.1126/scisignal.2001699
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7175159
mint:MINT-8258197
imex:IM-16799-928
Confidence scoreintact-miscore:0.37
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:SF2
comment:homomint
comment:mint
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:559292(yeast)
taxid:559292(Saccharomyces cerevisiae)
Parameters of the interaction-
Creation date2011/10/20
Update date2024/11/29
negative Boolean valuefalse
Feature(s) for interactor Afusion protein:?-?(MINT-8258201)
Feature(s) for interactor Bfusion protein:?-?(MINT-8258206)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BNucleotide sequence identification