| Unique identifier for interactor A | uniprotkb:P50750 |
| Unique identifier for interactor B | uniprotkb:O94992 |
| Alternative identifier for interactor A | intact:EBI-1383449 uniprotkb:Q5JU24 uniprotkb:Q5JU25 uniprotkb:Q5U006 uniprotkb:Q96TF1 ensembl:ENSP00000362361.4 intact:EBI-21360326 |
| Alternative identifier for interactor B | intact:EBI-2832510 uniprotkb:B2R8Y5 ensembl:ENSP00000328773.3 |
| Aliases for A | psi-mi:cdk9_human(display_long) uniprotkb:CDK9(gene name) psi-mi:CDK9(display_short) uniprotkb:CDC2L4(gene name synonym) uniprotkb:Cell division protein kinase 9(gene name synonym) uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym) uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym) uniprotkb:C-2K(gene name synonym) uniprotkb:TAK(gene name synonym) uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) |
| Aliases for B | psi-mi:hexi1_human(display_long) uniprotkb:HEXIM1(gene name) psi-mi:HEXIM1(display_short) uniprotkb:CLP1(gene name synonym) uniprotkb:EDG1(gene name synonym) uniprotkb:HIS1(gene name synonym) uniprotkb:MAQ1(gene name synonym) uniprotkb:Cardiac lineage protein 1(gene name synonym) uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym) uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym) uniprotkb:Menage a quatre protein 1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Ammosova et al. (2011) |
| Identifier of the publication | mint:MINT-8208521 pubmed:21533037 doi:10.1371/journal.pone.0018985 imex:IM-26457 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8662289 mint:MINT-8208529 imex:IM-26457-1 |
| Confidence score | intact-miscore:0.93 |
| Complex expansion | psi-mi:"MI:1060"(spoke expansion) |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Bait |
| Experimental role B | Prey |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:When phosphatase activity was inhibited in the cell, the wild-type CDK9 showed decreased association with cyclin T1 and increased with HEXIM1. Under these conditions, CDK9 Ser175Ala showed decreased association with cyclin T1, CDK9 Ser175Asp mutant had an increase in thebinding to cyclin T1, but decreased to HEXIM1 figure legend:f6b comment:homomint comment:mint full coverage:Only protein-protein interactions partial coverage:partial coverage curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human) taxid:9606(Homo sapiens) |
| Parameters of the interaction | - |
| Creation date | 2011/09/28 |
| Update date | 2024/11/15 |
| negative Boolean value | false |
| Feature(s) for interactor A | flag tag:?-?(MINT-8208534) mutation with no effect:175-175 mutation with no effect:175-175 |
| Feature(s) for interactor B | - |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Western blot |