Curation Details
Interaction ID: MINT-8206789

Unique identifier for interactor Auniprotkb:Q07954
Unique identifier for interactor Buniprotkb:P05067-4
Alternative identifier for interactor Aintact:EBI-1046087
uniprotkb:Q8IVG8
uniprotkb:Q2PP12
ensembl:ENSP00000243077.3
uniprotkb:Q86SW0
Alternative identifier for interactor Bintact:EBI-302641
intact:EBI-8513344
intact:MINT-150885
intact:EBI-8513450
intact:EBI-8513789
intact:EBI-7458081
intact:EBI-7458225
intact:EBI-8513738
intact:EBI-8513677
intact:EBI-8513407
intact:EBI-7457926
ensembl:ENSP00000345463.5
Aliases for Apsi-mi:lrp1_human(display_long)
uniprotkb:Alpha-2-macroglobulin receptor(gene name synonym)
uniprotkb:Apolipoprotein E receptor(gene name synonym)
uniprotkb:LRP1(gene name)
psi-mi:LRP1(display_short)
uniprotkb:A2MR(gene name synonym)
uniprotkb:APR(gene name synonym)
Aliases for Bpsi-mi:p05067-4(display_long)
uniprotkb:APP(gene name)
psi-mi:APP(display_short)
uniprotkb:A4(gene name synonym)
uniprotkb:AD1(gene name synonym)
uniprotkb:ABPP(gene name synonym)
uniprotkb:Alzheimer disease amyloid protein(gene name synonym)
uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)
uniprotkb:PreA4(gene name synonym)
uniprotkb:Protease nexin-II(gene name synonym)
uniprotkb:APPI(gene name synonym)
uniprotkb:PreA4 695(isoform synonym)
uniprotkb:Amyloid precursor protein(gene name synonym)
uniprotkb:Amyloid-beta A4 protein(gene name synonym)
uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)
uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorKlug et al. (2011)
Identifier of the publicationpubmed:21968187
imex:IM-16790
mint:MINT-8206639
doi:10.1016/j.febslet.2011.09.028
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-7458074
mint:MINT-8206789
imex:IM-16790-5
Confidence scoreintact-miscore:0.40
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f5a
comment:homomint
comment:domino
comment:mint
dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2011/09/23
Update date2024/11/12
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:4445-4544(MINT-8206807)
phosphorylated residue:4507-4507(MINT-8206803)
glutathione s tranferase tag:?-?(MINT-8206805)
Feature(s) for interactor Btag:?-?(MINT-8206816)
binding-associated region:664-695(MINT-8206819)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BWestern blot