Curation Details
Interaction ID: MINT-8205525

Unique identifier for interactor Auniprotkb:P28482
Unique identifier for interactor Buniprotkb:Q99759
Alternative identifier for interactor Aintact:EBI-959949
uniprotkb:A8CZ64
ensembl:ENSP00000215832.7
ensembl:ENSP00000381803.3
Alternative identifier for interactor Bintact:EBI-307281
uniprotkb:Q5BKZ6
intact:EBI-1384243
uniprotkb:B2RCW2
uniprotkb:Q8N3I9
uniprotkb:D3DU15
ensembl:ENSP00000354485.4
Aliases for Apsi-mi:mk01_human(display_long)
uniprotkb:MAPK1(gene name)
psi-mi:MAPK1(display_short)
uniprotkb:ERK2(gene name synonym)
uniprotkb:PRKM1(gene name synonym)
uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)
uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)
uniprotkb:MAP kinase isoform p42(gene name synonym)
uniprotkb:ERT1(gene name synonym)
uniprotkb:PRKM2(gene name synonym)
Aliases for Bpsi-mi:m3k3_human(display_long)
uniprotkb:MAP3K3(gene name)
psi-mi:MAP3K3(display_short)
uniprotkb:MAPKKK3(gene name synonym)
uniprotkb:MEKK3(gene name synonym)
uniprotkb:MAPK/ERK kinase kinase 3(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorFritz et al. (2006)
Identifier of the publicationpubmed:16407301
mint:MINT-8007293
doi:10.1074/jbc.M509249200
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8000656
mint:MINT-8205525
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:F2
comment:mint
partial coverage:partial coverage
NCBI Taxonomy identifier for the host organismtaxid:9606(human)
taxid:9606(Homo sapiens)
Parameters of the interaction-
Creation date2010/09/21
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bmutation disrupting interaction:391-391(MINT-8205537)
mutation disrupting interaction:530-530(MINT-8205543)
mutation disrupting interaction:526-526(MINT-8205540)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant