| Unique identifier for interactor A | uniprotkb:Q15797 |
| Unique identifier for interactor B | uniprotkb:Q9HCE7-2 |
| Alternative identifier for interactor A | intact:EBI-1567153 ensembl:ENSP00000305769.4 ensembl:ENSP00000377652.2 ensembl:ENSP00000426568.1 uniprotkb:D3DNZ9 uniprotkb:A8KAJ0 uniprotkb:Q9UFT8 uniprotkb:Q16636 |
| Alternative identifier for interactor B | intact:EBI-9845742 ensembl:ENSP00000355326.2 |
| Aliases for A | psi-mi:smad1_human(display_long) uniprotkb:Mad-related protein 1(gene name synonym) uniprotkb:SMAD family member 1(gene name synonym) uniprotkb:Transforming growth factor-beta-signaling protein 1(gene name synonym) uniprotkb:JV4-1(gene name synonym) uniprotkb:SMAD1(gene name) psi-mi:SMAD1(display_short) uniprotkb:BSP1(gene name synonym) uniprotkb:MADH1(gene name synonym) uniprotkb:MADR1(gene name synonym) |
| Aliases for B | psi-mi:q9hce7-2(display_long) uniprotkb:HECT-type E3 ubiquitin transferase SMURF1(gene name synonym) uniprotkb:SMURF1(gene name) psi-mi:SMURF1(display_short) uniprotkb:KIAA1625(gene name synonym) uniprotkb:SMAD ubiquitination regulatory factor 1(gene name synonym) uniprotkb:SMAD-specific E3 ubiquitin-protein ligase 1(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0096"(pull down) |
| First author | Tian et al. (2011) |
| Identifier of the publication | pubmed:21708152 mint:MINT-8187334 doi:10.1016/j.febslet.2011.06.016 imex:IM-23216 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-6996779 imex:IM-23216-4 mint:MINT-8187375 |
| Confidence score | intact-miscore:0.54 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:homomint comment:domino comment:mint figure legend:f2a f2e causality statement:Q9HCE7-2 increases degradation at protein level of Q15797 causality statement:Q9HCE7-2 is required for ubiquitination of Q15797 dataset:IBD - Inflammatory bowel disease full coverage:Only protein-protein interactions curation depth:imex curation |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2011/06/16 |
| Update date | 2014/10/16 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | necessary binding region:160-345(MINT-8187384) glutathione s tranferase tag:n-n(MINT-8187382) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Predetermined participant |