Curation Details
Interaction ID: MINT-8182931

Unique identifier for interactor Auniprotkb:P10600
Unique identifier for interactor Buniprotkb:P36897
Alternative identifier for interactor Aintact:EBI-1033020
uniprotkb:Q8WV88
ensembl:ENSP00000238682.3
ensembl:ENSP00000502685.1
Alternative identifier for interactor Bintact:EBI-1027557
uniprotkb:Q6IR47
uniprotkb:Q706C0
uniprotkb:Q706C1
ensembl:ENSP00000364133.4
Aliases for Apsi-mi:tgfb3_human(display_long)
uniprotkb:TGFB3(gene name)
psi-mi:TGFB3(display_short)
Aliases for Bpsi-mi:tgfr1_human(display_long)
uniprotkb:TGFBR1(gene name)
psi-mi:TGFBR1(display_short)
uniprotkb:Transforming growth factor-beta receptor type I(gene name synonym)
uniprotkb:TGF-beta type I receptor(gene name synonym)
uniprotkb:Serine/threonine-protein kinase receptor R4(gene name synonym)
uniprotkb:Activin receptor-like kinase 5(gene name synonym)
uniprotkb:ALK5(gene name synonym)
uniprotkb:SKR4(gene name synonym)
uniprotkb:Activin A receptor type II-like protein kinase of 53kD(gene name synonym)
Interaction detection methodspsi-mi:"MI:0226"(ion exchange chromatography)
First authorHuang et al. (2011)
Identifier of the publicationmint:MINT-8176542
pubmed:21423151
imex:IM-15413
doi:10.1038/emboj.2011.54
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8616034
mint:MINT-8182931
imex:IM-15413-9
Confidence scoreintact-miscore:0.63
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role AUnspecified role
Experimental role BUnspecified role
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:6d sf3 tiii
causality statement:P10600 increases activity of P36897
causality statement:P10600 increases activity of P37173
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2011/05/19
Update date2024/11/28
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bbinding-associated region:7-91(MINT-8182943)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BPredetermined participant