Curation Details
Interaction ID: MINT-8182828

Unique identifier for interactor Auniprotkb:P10600
Unique identifier for interactor Buniprotkb:P36897
Alternative identifier for interactor Aintact:EBI-1033020
ensembl:ENSP00000238682.3
ensembl:ENSP00000502685.1
uniprotkb:Q8WV88
Alternative identifier for interactor Bintact:EBI-1027557
uniprotkb:Q6IR47
uniprotkb:Q706C0
uniprotkb:Q706C1
ensembl:ENSP00000364133.4
Aliases for Apsi-mi:tgfb3_human(display_long)
uniprotkb:TGFB3(gene name)
psi-mi:TGFB3(display_short)
Aliases for Bpsi-mi:tgfr1_human(display_long)
uniprotkb:TGFBR1(gene name)
psi-mi:TGFBR1(display_short)
uniprotkb:Transforming growth factor-beta receptor type I(gene name synonym)
uniprotkb:TGF-beta type I receptor(gene name synonym)
uniprotkb:Serine/threonine-protein kinase receptor R4(gene name synonym)
uniprotkb:Activin receptor-like kinase 5(gene name synonym)
uniprotkb:ALK5(gene name synonym)
uniprotkb:SKR4(gene name synonym)
uniprotkb:Activin A receptor type II-like protein kinase of 53kD(gene name synonym)
Interaction detection methodspsi-mi:"MI:0276"(blue native page)
First authorHuang et al. (2011)
Identifier of the publicationmint:MINT-8176542
pubmed:21423151
imex:IM-15413
doi:10.1038/emboj.2011.54
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8616141
mint:MINT-8182828
imex:IM-15413-7
Confidence scoreintact-miscore:0.63
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:f3b f6c
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2011/05/19
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Amutation disrupting interaction:390-390(MINT-8182998)
mutation disrupting interaction:394-394(MINT-8183000)
mutation disrupting interaction:325-325(MINT-8182996)
Feature(s) for interactor Bbinding-associated region:7-91(MINT-8182843)
Stoichiometry for interactor A2
Stoichiometry for interactor B1
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BMolecular weight estimation by coomasie staining