Curation Details
Interaction ID: MINT-8177907

Unique identifier for interactor Auniprotkb:P31749
Unique identifier for interactor Buniprotkb:Q5S007
Alternative identifier for interactor Aintact:EBI-296087
uniprotkb:Q9BWB6
uniprotkb:B2RAM5
ensembl:ENSP00000270202.4
ensembl:ENSP00000384293.2
ensembl:ENSP00000385326.2
ensembl:ENSP00000450688.1
ensembl:ENSP00000451166.1
ensembl:ENSP00000451828.1
ensembl:ENSP00000497822.1
ensembl:ENSP00000507879.1
uniprotkb:B7Z5R1
Alternative identifier for interactor Bintact:EBI-5323863
uniprotkb:A6NJU2
uniprotkb:Q6ZS50
uniprotkb:Q8NCX9
ensembl:ENSP00000298910.7
intact:EBI-28978369
Aliases for Apsi-mi:akt1_human(display_long)
uniprotkb:AKT1(gene name)
psi-mi:AKT1(display_short)
uniprotkb:PKB(gene name synonym)
uniprotkb:RAC(gene name synonym)
uniprotkb:RAC-PK-alpha(gene name synonym)
uniprotkb:Protein kinase B(gene name synonym)
uniprotkb:Proto-oncogene c-Akt(gene name synonym)
uniprotkb:Protein kinase B alpha(gene name synonym)
Aliases for Bpsi-mi:lrrk2_human(display_long)
uniprotkb:LRRK2(gene name)
psi-mi:LRRK2(display_short)
uniprotkb:PARK8(gene name synonym)
uniprotkb:Dardarin(gene name synonym)
Interaction detection methodspsi-mi:"MI:0424"(protein kinase assay)
First authorOhta et al. (2011)
Identifier of the publicationpubmed:21658387
imex:IM-16740
mint:MINT-8177860
doi:10.1016/j.febslet.2011.05.044
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0217"(phosphorylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-6975501
mint:MINT-8177907
imex:IM-16740-6
Confidence scoreintact-miscore:0.56
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:f1a f2 f5a f5b
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2011/05/16
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor Ahis tag:?-?(MINT-8177910)
phosphorylated residue:473-473(MINT-8177912)
Feature(s) for interactor Bglutathione s tranferase tag:?-?(MINT-8177948)
mutation decreasing interaction:2020-2020(MINT-8177918)
binding-associated region:970-2527(MINT-8177916)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMolecular weight estimation by autoradiography
Participant identification method for interactor BPredetermined participant