Curation Details
Interaction ID: MINT-8152009

Unique identifier for interactor Auniprotkb:P51693
Unique identifier for interactor Buniprotkb:Q93074
Alternative identifier for interactor Aintact:EBI-74648
uniprotkb:O00113
uniprotkb:Q96A92
ensembl:ENSP00000498366.1
Alternative identifier for interactor Bintact:EBI-394357
uniprotkb:O15410
uniprotkb:O75557
uniprotkb:Q9UHV6
uniprotkb:Q9UND7
ensembl:ENSP00000363193.3
Aliases for Apsi-mi:aplp1_human(display_long)
uniprotkb:APLP1(gene name)
psi-mi:APLP1(display_short)
uniprotkb:"Amyloid beta (A4) precursor-like protein 1"(gene name synonym)
uniprotkb:Amyloid-like protein 1(gene name synonym)
Aliases for Bpsi-mi:med12_human(display_long)
uniprotkb:TRAP230(gene name synonym)
uniprotkb:MED12(gene name)
psi-mi:MED12(display_short)
uniprotkb:ARC240(gene name synonym)
uniprotkb:CAGH45(gene name synonym)
uniprotkb:HOPA(gene name synonym)
uniprotkb:KIAA0192(gene name synonym)
uniprotkb:Mediator complex subunit 12(gene name synonym)
uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)
uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)
uniprotkb:CAG repeat protein 45(gene name synonym)
uniprotkb:OPA-containing protein(gene name synonym)
uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)
uniprotkb:TNRC11(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorXu et al. (2011)
Identifier of the publicationmint:MINT-8151555
pubmed:21293490
imex:IM-15370
doi:10.1038/embor.2010.210
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8580521
mint:MINT-8152009
imex:IM-15370-4
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:domino
comment:mint
figure legend:sf2b sf2c
dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2011/04/04
Update date2024/11/30
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?(MINT-8152015)
binding-associated region:591-650(MINT-8152018)
Feature(s) for interactor Bbinding-associated region:1616-2050(IPR021989)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BMolecular weight estimation by autoradiography