Curation Details
Interaction ID: MINT-8151975

Unique identifier for interactor Auniprotkb:P05067
Unique identifier for interactor Buniprotkb:Q93074
Alternative identifier for interactor Aintact:EBI-77613
uniprotkb:P09000
uniprotkb:P78438
uniprotkb:Q13764
uniprotkb:Q13778
uniprotkb:Q13793
intact:EBI-28985182
uniprotkb:Q6GSC0
uniprotkb:Q8WZ99
uniprotkb:Q9UC33
uniprotkb:Q9UCC8
uniprotkb:Q9UCD1
uniprotkb:Q9UQ58
uniprotkb:Q16011
uniprotkb:Q16014
uniprotkb:Q16019
uniprotkb:Q16020
uniprotkb:Q9BT38
uniprotkb:Q9UCA9
uniprotkb:Q9UCB6
uniprotkb:B4DII8
uniprotkb:B2R5V1
uniprotkb:D3DSD1
uniprotkb:D3DSD2
uniprotkb:D3DSD3
ensembl:ENSP00000284981.4
Alternative identifier for interactor Bintact:EBI-394357
uniprotkb:O15410
uniprotkb:O75557
uniprotkb:Q9UHV6
uniprotkb:Q9UND7
ensembl:ENSP00000363193.3
Aliases for Apsi-mi:a4_human(display_long)
uniprotkb:APP(gene name)
psi-mi:APP(display_short)
uniprotkb:A4(gene name synonym)
uniprotkb:AD1(gene name synonym)
uniprotkb:Alzheimer disease amyloid protein(gene name synonym)
uniprotkb:ABPP(gene name synonym)
uniprotkb:PreA4(gene name synonym)
uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)
uniprotkb:Protease nexin-II(gene name synonym)
uniprotkb:APPI(gene name synonym)
uniprotkb:Amyloid precursor protein(gene name synonym)
uniprotkb:Amyloid-beta A4 protein(gene name synonym)
uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)
uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)
Aliases for Bpsi-mi:med12_human(display_long)
uniprotkb:TRAP230(gene name synonym)
uniprotkb:MED12(gene name)
psi-mi:MED12(display_short)
uniprotkb:ARC240(gene name synonym)
uniprotkb:CAGH45(gene name synonym)
uniprotkb:HOPA(gene name synonym)
uniprotkb:KIAA0192(gene name synonym)
uniprotkb:Mediator complex subunit 12(gene name synonym)
uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)
uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)
uniprotkb:CAG repeat protein 45(gene name synonym)
uniprotkb:OPA-containing protein(gene name synonym)
uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)
uniprotkb:TNRC11(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorXu et al. (2011)
Identifier of the publicationmint:MINT-8151555
pubmed:21293490
imex:IM-15370
doi:10.1038/embor.2010.210
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8580473
mint:MINT-8151975
imex:IM-15370-2
Confidence scoreintact-miscore:0.44
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role APrey
Experimental role BBait
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:sf1b sf1d
dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2011/04/04
Update date2024/11/30
negative Boolean valuefalse
Feature(s) for interactor Afusion protein:?-?(MINT-8151984)
binding-associated region:721-770(MINT-8151986)
Feature(s) for interactor Bglutathione s tranferase tag:?-?(MINT-8151980)
binding-associated region:1616-2177(MINT-8151978)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AMolecular weight estimation by autoradiography
Participant identification method for interactor BPredetermined participant