Curation Details
Interaction ID: MINT-8151905

Unique identifier for interactor Auniprotkb:Q9NPJ6
Unique identifier for interactor Buniprotkb:P05067
Alternative identifier for interactor Aintact:EBI-394607
uniprotkb:Q9BS95
uniprotkb:Q9NYR5
uniprotkb:Q53GB4
uniprotkb:Q53H68
uniprotkb:Q5T912
uniprotkb:Q6FHC4
uniprotkb:Q6IA79
uniprotkb:B4DX67
ensembl:ENSP00000258648.2
Alternative identifier for interactor Bintact:EBI-77613
uniprotkb:P09000
uniprotkb:P78438
uniprotkb:Q13764
uniprotkb:Q13778
uniprotkb:Q13793
intact:EBI-28985182
uniprotkb:Q6GSC0
uniprotkb:Q8WZ99
uniprotkb:Q9UC33
uniprotkb:Q9UCC8
uniprotkb:Q9UCD1
uniprotkb:Q9UQ58
uniprotkb:Q16011
uniprotkb:Q16014
uniprotkb:Q16019
uniprotkb:Q16020
uniprotkb:Q9BT38
uniprotkb:Q9UCA9
uniprotkb:Q9UCB6
uniprotkb:B4DII8
uniprotkb:B2R5V1
uniprotkb:D3DSD1
uniprotkb:D3DSD2
uniprotkb:D3DSD3
ensembl:ENSP00000284981.4
Aliases for Apsi-mi:med4_human(display_long)
uniprotkb:HSPC126(orf name)
uniprotkb:DRIP36(gene name synonym)
uniprotkb:MED4(gene name)
psi-mi:MED4(display_short)
uniprotkb:ARC36(gene name synonym)
uniprotkb:Mediator complex subunit 4(gene name synonym)
uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)
uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)
uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)
uniprotkb:VDRIP(gene name synonym)
Aliases for Bpsi-mi:a4_human(display_long)
uniprotkb:APP(gene name)
psi-mi:APP(display_short)
uniprotkb:A4(gene name synonym)
uniprotkb:AD1(gene name synonym)
uniprotkb:Alzheimer disease amyloid protein(gene name synonym)
uniprotkb:ABPP(gene name synonym)
uniprotkb:PreA4(gene name synonym)
uniprotkb:Cerebral vascular amyloid peptide(gene name synonym)
uniprotkb:Protease nexin-II(gene name synonym)
uniprotkb:APPI(gene name synonym)
uniprotkb:Amyloid precursor protein(gene name synonym)
uniprotkb:Amyloid-beta A4 protein(gene name synonym)
uniprotkb:Alzheimer disease amyloid A4 protein homolog(gene name synonym)
uniprotkb:"Amyloid-beta (A4) precursor protein"(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorXu et al. (2011)
Identifier of the publicationmint:MINT-8151555
pubmed:21293490
imex:IM-15370
doi:10.1038/embor.2010.210
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0914"(association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8580402
mint:MINT-8151905
imex:IM-15370-10
Confidence scoreintact-miscore:0.35
Complex expansionpsi-mi:"MI:1060"(spoke expansion)
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f1e
comment:homomint
comment:mint
dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-hela)
taxid:9606(Homo sapiens HeLa epitheloid cervical carcinoma cell)
Parameters of the interaction-
Creation date2011/04/04
Update date2024/11/12
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bbinding-associated region:721-770(MINT-8151926)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BWestern blot