Curation Details
Interaction ID: MINT-8146425

Unique identifier for interactor Auniprotkb:P00533
Unique identifier for interactor Buniprotkb:P01133
Alternative identifier for interactor Aintact:EBI-297353
uniprotkb:Q9BZS2
uniprotkb:Q9GZX1
uniprotkb:Q9H2C9
uniprotkb:Q9H3C9
uniprotkb:Q9UMD7
uniprotkb:Q9UMD8
uniprotkb:Q9UMG5
uniprotkb:O00688
uniprotkb:O00732
uniprotkb:P06268
uniprotkb:Q14225
uniprotkb:Q92795
intact:EBI-28985169
uniprotkb:Q68GS5
ensembl:ENSP00000275493.2
Alternative identifier for interactor Bintact:EBI-640857
uniprotkb:B4DRK7
uniprotkb:E9PBF0
uniprotkb:Q52LZ6
uniprotkb:E7EVD2
ensembl:ENSP00000265171.5
Aliases for Apsi-mi:egfr_human(display_long)
uniprotkb:ERBB1(gene name synonym)
uniprotkb:EGFR(gene name)
psi-mi:EGFR(display_short)
uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)
uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)
uniprotkb:ERBB(gene name synonym)
uniprotkb:HER1(gene name synonym)
Aliases for Bpsi-mi:egf_human(display_long)
uniprotkb:EGF(gene name)
psi-mi:EGF(display_short)
Interaction detection methodspsi-mi:"MI:0054"(fluorescence-activated cell sorting)
First authorLahti et al. (2011)
Identifier of the publicationmint:MINT-8145580
pubmed:21439278
imex:IM-15852
doi:10.1016/j.febslet.2011.03.044
mint:d-10-02080
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8619069
mint:MINT-8146425
imex:IM-15852-10
Confidence scoreintact-miscore:0.97
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:f1b f3b t2
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-bj)
taxid:9606(Homo sapiens BJ foreskin fibroblast cell)
Parameters of the interactionkd:34.0x10^-12(molar)
Creation date2011/03/21
Update date2024/09/12
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bflag tag:?-?(MINT-8146447)
mutation increasing interaction:973-973,978-978,980-980,991-991,998-998,1021-1022,1008-1008,1018-1018(MINT-8146443)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor APredetermined participant
Participant identification method for interactor BIdentification by antibody