| Unique identifier for interactor A | uniprotkb:P04147 |
| Unique identifier for interactor B | uniprotkb:P39935 |
| Alternative identifier for interactor A | intact:EBI-12823 uniprotkb:D3DM73 |
| Alternative identifier for interactor B | intact:EBI-9002 uniprotkb:D6VUU6 |
| Aliases for A | psi-mi:pabp_yeast(display_long) uniprotkb:PAB1(gene name) psi-mi:PAB1(display_short) uniprotkb:ARS consensus-binding protein ACBP-67(gene name synonym) uniprotkb:Polyadenylate tail-binding protein(gene name synonym) uniprotkb:YER165W(locus name) |
| Aliases for B | psi-mi:if4f1_yeast(display_long) uniprotkb:YGR162W(locus name) uniprotkb:TIF4631(gene name) psi-mi:TIF4631(display_short) uniprotkb:eIF4G1(gene name synonym) uniprotkb:mRNA cap-binding protein complex subunit p150(gene name synonym) uniprotkb:"Translation initiation factor 4(4)-F(6) subunit gamma(3) protein 1"(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0007"(anti tag coimmunoprecipitation) |
| First author | Park et al. (2011) |
| Identifier of the publication | mint:MINT-8114863 pubmed:21139564 imex:IM-15350 doi:10.1038/emboj.2010.312 |
| NCBI Taxonomy identifier for interactor A | taxid:559292(yeast) taxid:559292(Saccharomyces cerevisiae) |
| NCBI Taxonomy identifier for interactor B | taxid:559292(yeast) taxid:559292(Saccharomyces cerevisiae) |
| Interaction types | psi-mi:"MI:0914"(association) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8535463 mint:MINT-8115060 imex:IM-15350-5 |
| Confidence score | intact-miscore:0.93 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Prey |
| Experimental role B | Bait |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:f5D comment:"\"Eliminating the canonical PABP-binding domain of eIF4G1 is not sufficient for synthetic lethality with the −459 mutation in the eIF4E-binding site. Rather, the extreme N-terminus of eIF4G1 (aa 1-82), which has RNA-binding activity must be removed together with the PABP-binding domain to produce a lethal reduction in the function of the eIF4G1-459 mutant protein\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:559292(yeast) taxid:559292(Saccharomyces cerevisiae) |
| Parameters of the interaction | - |
| Creation date | 2011/02/21 |
| Update date | 2025/03/11 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | ha tag:?-?(MINT-8115067) mutation decreasing interaction:457-457(MINT-8115065) mutation decreasing interaction:458-458(MINT-8115063) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Western blot |
| Participant identification method for interactor B | Anti tag western blot |