Curation Details
Interaction ID: MINT-8086425

Unique identifier for interactor Auniprotkb:Q12888
Unique identifier for interactor Buniprotkb:Q92547
Alternative identifier for interactor Aintact:EBI-396540
uniprotkb:Q2M1Z7
uniprotkb:Q4LE46
uniprotkb:Q5FWZ3
uniprotkb:Q7Z3U4
uniprotkb:F8VY86
ensembl:ENSP00000263801.3
Alternative identifier for interactor Bintact:EBI-308302
uniprotkb:Q7LGC1
uniprotkb:Q9UEB9
uniprotkb:B7Z7W8
ensembl:ENSP00000260810.5
Aliases for Apsi-mi:tp53b_human(display_long)
uniprotkb:TP53BP1(gene name)
psi-mi:TP53BP1(display_short)
Aliases for Bpsi-mi:topb1_human(display_long)
uniprotkb:KIAA0259(gene name synonym)
uniprotkb:TOPBP1(gene name)
psi-mi:TOPBP1(display_short)
uniprotkb:DNA topoisomerase II-binding protein 1(gene name synonym)
uniprotkb:DNA topoisomerase II-beta-binding protein 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0416"(fluorescence microscopy)
First authorCescutti et al. (2010)
Identifier of the publicationdoi:10.1038/emboj.2010.238
pubmed:20871591
imex:IM-15353
mint:MINT-8086392
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0403"(colocalization)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8344141
mint:MINT-8086425
imex:IM-15353-6
Confidence scoreintact-miscore:0.45
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:domino
comment:mint
figure legend:f2b f3a
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-u2os)
taxid:9606(Homo sapiens U2OS osteosarcoma cell)
Parameters of the interaction-
Creation date2011/01/20
Update date2024/11/14
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bgreen fluorescent protein tag:?-?(MINT-8086434)
binding-associated region:531-755(MINT-8086431)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AImmunostaining
Participant identification method for interactor BTag visualisation by fluorescence