Curation Details
Interaction ID: MINT-8084841

Unique identifier for interactor Auniprotkb:Q9H2K2
Unique identifier for interactor Buniprotkb:Q9NWT6
Alternative identifier for interactor Aintact:EBI-4398527
uniprotkb:B2RBD3
ensembl:ENSP00000360689.4
uniprotkb:Q9H8F2
uniprotkb:Q9HAS4
Alternative identifier for interactor Bintact:EBI-745632
uniprotkb:D3DR69
ensembl:ENSP00000299163.4
uniprotkb:Q969Q7
uniprotkb:Q9NPV5
uniprotkb:Q5W147
Aliases for Apsi-mi:tnks2_human(display_long)
uniprotkb:TNKS2(gene name)
psi-mi:TNKS2(display_short)
uniprotkb:PARP5B(gene name synonym)
uniprotkb:TANK2(gene name synonym)
uniprotkb:TNKL(gene name synonym)
uniprotkb:Poly [ADP-ribose] polymerase 5B(gene name synonym)
uniprotkb:TNKS-2(gene name synonym)
uniprotkb:TRF1-interacting ankyrin-related ADP-ribose polymerase 2(gene name synonym)
uniprotkb:Tankyrase II(gene name synonym)
uniprotkb:Tankyrase-like protein(gene name synonym)
uniprotkb:Tankyrase-related protein(gene name synonym)
uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 6(gene name synonym)
uniprotkb:Protein poly-ADP-ribosyltransferase tankyrase-2(gene name synonym)
uniprotkb:Tankyrase-2(gene name synonym)
Aliases for Bpsi-mi:hif1n_human(display_long)
uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)
uniprotkb:Factor inhibiting HIF-1(gene name synonym)
uniprotkb:HIF1AN(gene name)
psi-mi:HIF1AN(display_short)
uniprotkb:FIH1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0415"(enzymatic study)
First authorYang et al. (2011)
Identifier of the publicationmint:MINT-8084809
pubmed:21251231
doi:10.1111/j.1742-4658.2011.08022
mint:fj-10-1159
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0210"(hydroxylation reaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8565717
mint:MINT-8084841
Confidence scoreintact-miscore:0.74
Complex expansion-
Biological role AEnzyme target
Biological role BEnzyme
Experimental role ANeutral component
Experimental role BNeutral component
Interactor type AProtein
Interactor type BProtein
Annotations for the interactioncomment:homomint
comment:mint
figure legend:f1b sf1 f4 sf5
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2011/01/11
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor Abinding-associated region:538-558(MINT-8084847)
dihydroxylated residue:553-553(MINT-8084845)
mutation increasing interaction:553-553(MINT-8084953)
Feature(s) for interactor B-
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AIdentification by mass spectrometry
Participant identification method for interactor BPredetermined participant