| Unique identifier for interactor A | uniprotkb:P05412 |
| Unique identifier for interactor B | uniprotkb:P01100 |
| Alternative identifier for interactor A | intact:EBI-852823 uniprotkb:Q96G93 uniprotkb:Q6FHM7 ensembl:ENSP00000360266.2 ensembl:ENSP00000503132.1 |
| Alternative identifier for interactor B | intact:EBI-852851 uniprotkb:P18849 uniprotkb:A8K4E2 uniprotkb:B4DQ65 ensembl:ENSP00000306245.4 |
| Aliases for A | psi-mi:jun_human(display_long) uniprotkb:Transcription factor AP-1 subunit Jun(gene name synonym) uniprotkb:JUN(gene name) psi-mi:JUN(display_short) uniprotkb:Activator protein 1(gene name synonym) uniprotkb:Proto-oncogene c-Jun(gene name synonym) uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym) uniprotkb:p39(gene name synonym) |
| Aliases for B | psi-mi:fos_human(display_long) uniprotkb:Cellular oncogene fos(gene name synonym) uniprotkb:G0/G1 switch regulatory protein 7(gene name synonym) uniprotkb:FOS(gene name) psi-mi:FOS(display_short) uniprotkb:G0S7(gene name synonym) uniprotkb:Proto-oncogene c-Fos(gene name synonym) uniprotkb:Transcription factor AP-1 subunit c-Fos(gene name synonym) uniprotkb:Fos proto-oncogene, AP-1 transcription factor subunit(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0065"(isothermal titration calorimetry) |
| First author | Worrall et al. (2011) |
| Identifier of the publication | mint:MINT-8077644 pubmed:21199371 mint:fj-10-1075 doi:10.1111/j.1742-4658.2010.07988 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0407"(direct interaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8554717 mint:MINT-8077811 |
| Confidence score | intact-miscore:0.97 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:homomint comment:mint comment:"\"JunW candi sequence: AAELEER AKTLKAE IYELRSK ANMLREH IAQL Analysis of the ITC data informs that, in agreement with thermal denaturation data, there is almost no change in the free energy of binding. However, dissection of this value into its thermodynamic components reveals JunWCANDI to have a slight increase in enthalpy change upon binding cFos (-14.8 vs. -13.9 kcal·mol-1), suggesting that more non-covalent bonds have been formed.\"" figure legend:t2 f2b f3 |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | kd:1.2x10^-6(molar) |
| Creation date | 2010/12/06 |
| Update date | 2024/09/12 |
| negative Boolean value | false |
| Feature(s) for interactor A | uncategorized protein modification:277-308(MINT-8077819) binding-associated region:277-308(MINT-8077821) |
| Feature(s) for interactor B | binding-associated region:162-193(MINT-8077815) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Peptide synthesis |
| Participant identification method for interactor B | Peptide synthesis |