Curation Details
Interaction ID: MINT-8058594

Unique identifier for interactor Auniprotkb:P22681
Unique identifier for interactor Buniprotkb:Q96B97
Alternative identifier for interactor Aintact:EBI-518228
ensembl:ENSP00000264033.3
uniprotkb:A3KMP8
Alternative identifier for interactor Bintact:EBI-346595
uniprotkb:Q8IWX6
uniprotkb:Q8IX98
uniprotkb:Q96RN4
uniprotkb:Q9NYR0
ensembl:ENSP00000380921.3
uniprotkb:B7Z1D5
uniprotkb:Q5JPT4
uniprotkb:Q5JPT5
Aliases for Apsi-mi:cbl_human(display_long)
uniprotkb:Signal transduction protein CBL(gene name synonym)
uniprotkb:Proto-oncogene c-Cbl(gene name synonym)
uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)
uniprotkb:RING finger protein 55(gene name synonym)
uniprotkb:CBL(gene name)
psi-mi:CBL(display_short)
uniprotkb:CBL2(gene name synonym)
uniprotkb:RNF55(gene name synonym)
uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym)
Aliases for Bpsi-mi:sh3k1_human(display_long)
uniprotkb:SH3KBP1(gene name)
psi-mi:SH3KBP1(display_short)
uniprotkb:CIN85(gene name synonym)
uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)
uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)
uniprotkb:CD2-binding protein 3(gene name synonym)
Interaction detection methodspsi-mi:"MI:0007"(anti tag coimmunoprecipitation)
First authorSchroeder et al. (2010)
Identifier of the publicationpubmed:20711168
imex:IM-15132
mint:MINT-8045116
doi:10.1038/emboj.2010.190
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8164979
imex:IM-15132-13
mint:MINT-8058594
Confidence scoreintact-miscore:0.97
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f6a
comment:homomint
comment:domino
comment:mint
curation depth:imex curation
full coverage:Only protein-protein interactions
NCBI Taxonomy identifier for the host organismtaxid:9606(human-huh7)
taxid:9606(Homo sapiens Huh7 hepatoma cell)
Parameters of the interaction-
Creation date2010/10/12
Update date2024/11/30
negative Boolean valuefalse
Feature(s) for interactor Aha tag:?-?(MINT-8058616)
Feature(s) for interactor Bflag tag:?-?(MINT-8058605)
mutation disrupting interaction:135-135(MINT-8058600)
binding-associated region:98-157(MINT-8058602)
mutation disrupting interaction:136-136(MINT-8058598)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot