| Unique identifier for interactor A | uniprotkb:P31749 |
| Unique identifier for interactor B | uniprotkb:O43524 |
| Alternative identifier for interactor A | intact:EBI-296087 uniprotkb:Q9BWB6 uniprotkb:B2RAM5 ensembl:ENSP00000270202.4 ensembl:ENSP00000384293.2 ensembl:ENSP00000385326.2 ensembl:ENSP00000450688.1 ensembl:ENSP00000451166.1 ensembl:ENSP00000451828.1 ensembl:ENSP00000497822.1 ensembl:ENSP00000507879.1 uniprotkb:B7Z5R1 |
| Alternative identifier for interactor B | intact:EBI-1644164 uniprotkb:Q9BZ04 uniprotkb:O15171 uniprotkb:Q5T2I7 ensembl:ENSP00000339527.6 ensembl:ENSP00000385824.1 uniprotkb:E1P5E6 uniprotkb:B4DVZ6 |
| Aliases for A | psi-mi:akt1_human(display_long) uniprotkb:AKT1(gene name) psi-mi:AKT1(display_short) uniprotkb:PKB(gene name synonym) uniprotkb:RAC(gene name synonym) uniprotkb:RAC-PK-alpha(gene name synonym) uniprotkb:Protein kinase B(gene name synonym) uniprotkb:Proto-oncogene c-Akt(gene name synonym) uniprotkb:Protein kinase B alpha(gene name synonym) |
| Aliases for B | psi-mi:foxo3_human(display_long) uniprotkb:FOXO3(gene name) psi-mi:FOXO3(display_short) uniprotkb:FKHRL1(gene name synonym) uniprotkb:FOXO3A(gene name synonym) uniprotkb:Forkhead in rhabdomyosarcoma-like 1(gene name synonym) uniprotkb:AF6q21 protein(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0424"(protein kinase assay) |
| First author | Brunet et al. (1999) |
| Identifier of the publication | pubmed:10102273 mint:MINT-5211323 imex:IM-27311 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0217"(phosphorylation reaction) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-6970438 mint:MINT-8005353 imex:IM-27311-3 |
| Confidence score | intact-miscore:0.69 |
| Complex expansion | - |
| Biological role A | Enzyme |
| Biological role B | Enzyme target |
| Experimental role A | Unspecified role |
| Experimental role B | Unspecified role |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | figure legend:Fig. 1 causality statement:"\"P31749 (GO:0004672) decreases activity of O43524 (GO:0001228)\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:-1(in vitro) taxid:-1(In vitro) |
| Parameters of the interaction | - |
| Creation date | 2003/01/20 |
| Update date | 2024/09/10 |
| negative Boolean value | false |
| Feature(s) for interactor A | ha tag:?-? mutation decreasing interaction rate:179-179 |
| Feature(s) for interactor B | glutathione s tranferase tag:?-? mutation with no effect:315-315 mutation decreasing interaction rate:32-32 mutation decreasing interaction rate:253-253 |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Predetermined participant |
| Participant identification method for interactor B | Predetermined participant |