| Unique identifier for interactor A | uniprotkb:P27824 |
| Unique identifier for interactor B | uniprotkb:Q99758 |
| Alternative identifier for interactor A | intact:EBI-355947 uniprotkb:D3DWQ3 uniprotkb:B2R5V8 ensembl:ENSP00000247461.4 ensembl:ENSP00000391646.2 ensembl:ENSP00000421434.2 ensembl:ENSP00000421813.2 ensembl:ENSP00000424063.1 ensembl:ENSP00000424745.2 ensembl:ENSP00000491760.1 ensembl:ENSP00000492372.1 ensembl:ENSP00000492868.1 ensembl:ENSP00000505013.1 ensembl:ENSP00000505202.1 ensembl:ENSP00000505526.1 ensembl:ENSP00000505960.1 ensembl:ENSP00000506003.1 ensembl:ENSP00000506021.1 ensembl:ENSP00000506061.1 ensembl:ENSP00000506078.1 ensembl:ENSP00000506509.1 ensembl:ENSP00000506568.1 ensembl:ENSP00000506583.1 intact:EBI-9513217 uniprotkb:B4DGP8 uniprotkb:B4E2T8 uniprotkb:D6R9K3 |
| Alternative identifier for interactor B | intact:EBI-8309859 uniprotkb:Q54A95 intact:MINT-6943242 uniprotkb:Q92473 uniprotkb:B2RU09 uniprotkb:Q6P5P9 intact:EBI-28973712 ensembl:ENSP00000301732.5 |
| Aliases for A | psi-mi:calx_human(display_long) uniprotkb:CANX(gene name) psi-mi:CANX(display_short) uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym) uniprotkb:p90(gene name synonym) uniprotkb:IP90(gene name synonym) |
| Aliases for B | psi-mi:abca3_human(display_long) uniprotkb:ABCA3(gene name) psi-mi:ABCA3(display_short) uniprotkb:ABC3(gene name synonym) uniprotkb:ATP-binding cassette transporter 3(gene name synonym) uniprotkb:ABC-C transporter(gene name synonym) uniprotkb:ATP-binding cassette sub-family A member 3(gene name synonym) uniprotkb:Xenobiotic-transporting ATPase ABCA3(gene name synonym) |
| Interaction detection methods | psi-mi:"MI:0416"(fluorescence microscopy) |
| First author | Engelbrecht et al. (2010) |
| Identifier of the publication | pubmed:20863830 imex:IM-15844 mint:MINT-7996358 doi:10.1016/j.febslet.2010.09.026 |
| NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
| NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
| Interaction types | psi-mi:"MI:0403"(colocalization) |
| Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
| Interaction identifier(s) in the corresponding source database | intact:EBI-8309967 mint:MINT-7996633 imex:IM-15844-4 |
| Confidence score | intact-miscore:0.27 |
| Complex expansion | - |
| Biological role A | Unspecified role |
| Biological role B | Unspecified role |
| Experimental role A | Neutral component |
| Experimental role B | Neutral component |
| Interactor type A | Protein |
| Interactor type B | Protein |
| Annotations for the interaction | comment:homomint comment:mint figure legend:4b comment:"\"Localization studies in A549 cells stably expressing WT, Q215K or E292V proteins with C-terminal HA-tag showed that the E292V mutant colocalized properly with the MVB/LB protein LAMP3 (Fig. 4A) but not with the ER protein calnexin (Fig. 4B). Q215K mutant remained in the ER compartment, overlapping with calnexin (Fig. 4B) and showing no colocalization with LAMP3 (Fig. 4A). Only mutated ABCA3 (Q215K) colocalize with Calnexin while wild-type ABCA3 only colocalizes with Calnexin while being processed and trafficked through the cell to its final destination.\"" curation depth:imex curation full coverage:Only protein-protein interactions |
| NCBI Taxonomy identifier for the host organism | taxid:9606(human-a_549) taxid:9606(Homo sapiens A549 lung carcinoma cell) |
| Parameters of the interaction | - |
| Creation date | 2010/09/14 |
| Update date | 2025/03/31 |
| negative Boolean value | false |
| Feature(s) for interactor A | - |
| Feature(s) for interactor B | mutation increasing interaction:215-215(MINT-7996639) ha tag:?-?(MINT-7996641) |
| Stoichiometry for interactor A | - |
| Stoichiometry for interactor B | - |
| Participant identification method for interactor A | Immunostaining |
| Participant identification method for interactor B | Anti tag immunostaining |