Unique identifier for interactor A | uniprotkb:P52294 |
Unique identifier for interactor B | uniprotkb:P00533 |
Alternative identifier for interactor A | intact:EBI-358383 uniprotkb:Q9BQ56 uniprotkb:Q6IBQ9 intact:EBI-1058734 uniprotkb:D3DN93 ensembl:ENSP00000343701.6 |
Alternative identifier for interactor B | intact:EBI-297353 uniprotkb:Q9BZS2 uniprotkb:Q9GZX1 uniprotkb:Q9H2C9 uniprotkb:Q9H3C9 uniprotkb:Q9UMD7 uniprotkb:Q9UMD8 uniprotkb:Q9UMG5 uniprotkb:O00688 uniprotkb:O00732 uniprotkb:P06268 uniprotkb:Q14225 uniprotkb:Q92795 intact:EBI-28985169 uniprotkb:Q68GS5 ensembl:ENSP00000275493.2 |
Aliases for A | psi-mi:ima5_human(display_long) uniprotkb:KPNA1(gene name) psi-mi:KPNA1(display_short) uniprotkb:RCH2(gene name synonym) uniprotkb:Karyopherin subunit alpha-1(gene name synonym) uniprotkb:SRP1-beta(gene name synonym) uniprotkb:RAG cohort protein 2(gene name synonym) uniprotkb:Nucleoprotein interactor 1(gene name synonym) |
Aliases for B | psi-mi:egfr_human(display_long) uniprotkb:ERBB1(gene name synonym) uniprotkb:EGFR(gene name) psi-mi:EGFR(display_short) uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym) uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym) uniprotkb:ERBB(gene name synonym) uniprotkb:HER1(gene name synonym) |
Interaction detection methods | psi-mi:"MI:0006"(anti bait coimmunoprecipitation) |
First author | Dittmann et al. (2010) |
Identifier of the publication | pubmed:20692258 imex:IM-15608 mint:MINT-7987951 doi:10.1016/j.febslet.2010.08.005 |
NCBI Taxonomy identifier for interactor A | taxid:9606(human) taxid:9606(Homo sapiens) |
NCBI Taxonomy identifier for interactor B | taxid:9606(human) taxid:9606(Homo sapiens) |
Interaction types | psi-mi:"MI:0915"(physical association) |
Source databases and identifiers | psi-mi:"MI:0471"(MINT) |
Interaction identifier(s) in the corresponding source database | intact:EBI-8109298 mint:MINT-7987956 imex:IM-15608-1 |
Confidence score | intact-miscore:0.40 |
Complex expansion | - |
Biological role A | Unspecified role |
Biological role B | Unspecified role |
Experimental role A | Bait |
Experimental role B | Prey |
Interactor type A | Protein |
Interactor type B | Protein |
Annotations for the interaction | figure legend:f4 comment:homomint comment:mint comment:"\"Karyopherin alpha has been detected endougenously expressed in Chinese Hamster (CHO-K1) cells by an antibody raised against the human isoform. Since its accession number needs to be updated we have used the human accession number.\"" curation depth:imex curation full coverage:Only protein-protein interactions |
NCBI Taxonomy identifier for the host organism | taxid:10029(crigr-cho_k1) taxid:10029(Cricetulus griseus ovary K1) |
Parameters of the interaction | - |
Creation date | 2010/08/02 |
Update date | 2024/09/12 |
negative Boolean value | false |
Feature(s) for interactor A | - |
Feature(s) for interactor B | mutation increasing interaction:654-654(MINT-7987966) mutation decreasing interaction:654-654(MINT-7988035) his tag:?-?(MINT-7987961) phosphorylated residue:654-654(MINT-7988033) |
Stoichiometry for interactor A | - |
Stoichiometry for interactor B | - |
Participant identification method for interactor A | Western blot |
Participant identification method for interactor B | Anti tag western blot |