Curation Details
Interaction ID: MINT-7987956

Unique identifier for interactor Auniprotkb:P52294
Unique identifier for interactor Buniprotkb:P00533
Alternative identifier for interactor Aintact:EBI-358383
uniprotkb:D3DN93
ensembl:ENSP00000343701.6
uniprotkb:Q9BQ56
uniprotkb:Q6IBQ9
intact:EBI-1058734
Alternative identifier for interactor Bintact:EBI-297353
uniprotkb:Q68GS5
ensembl:ENSP00000275493.2
uniprotkb:Q9BZS2
uniprotkb:Q9GZX1
uniprotkb:Q9H2C9
uniprotkb:Q9H3C9
uniprotkb:Q9UMD7
uniprotkb:Q9UMD8
uniprotkb:Q9UMG5
uniprotkb:O00688
uniprotkb:O00732
uniprotkb:P06268
uniprotkb:Q14225
uniprotkb:Q92795
intact:EBI-28985169
Aliases for Apsi-mi:ima5_human(display_long)
uniprotkb:KPNA1(gene name)
psi-mi:KPNA1(display_short)
uniprotkb:RCH2(gene name synonym)
uniprotkb:Karyopherin subunit alpha-1(gene name synonym)
uniprotkb:SRP1-beta(gene name synonym)
uniprotkb:RAG cohort protein 2(gene name synonym)
uniprotkb:Nucleoprotein interactor 1(gene name synonym)
Aliases for Bpsi-mi:egfr_human(display_long)
uniprotkb:ERBB1(gene name synonym)
uniprotkb:EGFR(gene name)
psi-mi:EGFR(display_short)
uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)
uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)
uniprotkb:ERBB(gene name synonym)
uniprotkb:HER1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0006"(anti bait coimmunoprecipitation)
First authorDittmann et al. (2010)
Identifier of the publicationpubmed:20692258
imex:IM-15608
mint:MINT-7987951
doi:10.1016/j.febslet.2010.08.005
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0915"(physical association)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8109298
mint:MINT-7987956
imex:IM-15608-1
Confidence scoreintact-miscore:0.40
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f4
comment:homomint
comment:mint
comment:"\"Karyopherin alpha has been detected endougenously expressed in Chinese Hamster (CHO-K1) cells by an antibody raised against the human isoform. Since its accession number needs to be updated we have used the human accession number.\""
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:10029(crigr-cho_k1)
taxid:10029(Cricetulus griseus ovary K1)
Parameters of the interaction-
Creation date2010/08/02
Update date2014/10/16
negative Boolean valuefalse
Feature(s) for interactor A-
Feature(s) for interactor Bmutation increasing interaction:654-654(MINT-7987966)
mutation decreasing interaction:654-654(MINT-7988035)
his tag:?-?(MINT-7987961)
phosphorylated residue:654-654(MINT-7988033)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AWestern blot
Participant identification method for interactor BAnti tag western blot