Curation Details
Interaction ID: MINT-7894271

Unique identifier for interactor Auniprotkb:Q9H160
Unique identifier for interactor Buniprotkb:Q9HCE7-2
Alternative identifier for interactor Aintact:EBI-389787
uniprotkb:B6ZDS1
ensembl:ENSP00000307183.3
uniprotkb:O95698
Alternative identifier for interactor Bintact:EBI-9845742
ensembl:ENSP00000355326.2
Aliases for Apsi-mi:ing2_human(display_long)
uniprotkb:ING2(gene name)
psi-mi:ING2(display_short)
uniprotkb:p33ING2(gene name synonym)
uniprotkb:Inhibitor of growth 1-like protein(gene name synonym)
uniprotkb:p32(gene name synonym)
uniprotkb:ING1L(gene name synonym)
Aliases for Bpsi-mi:q9hce7-2(display_long)
uniprotkb:HECT-type E3 ubiquitin transferase SMURF1(gene name synonym)
uniprotkb:SMURF1(gene name)
psi-mi:SMURF1(display_short)
uniprotkb:KIAA1625(gene name synonym)
uniprotkb:SMAD ubiquitination regulatory factor 1(gene name synonym)
uniprotkb:SMAD-specific E3 ubiquitin-protein ligase 1(gene name synonym)
Interaction detection methodspsi-mi:"MI:0096"(pull down)
First authorNie et al. (2010)
Identifier of the publicationpubmed:20621832
imex:IM-15593
mint:MINT-7894216
doi:10.1016/j.febslet.2010.05.033
mint:d-10-00566
NCBI Taxonomy identifier for interactor Ataxid:9606(human)
taxid:9606(Homo sapiens)
NCBI Taxonomy identifier for interactor Btaxid:9606(human)
taxid:9606(Homo sapiens)
Interaction typespsi-mi:"MI:0407"(direct interaction)
Source databases and identifierspsi-mi:"MI:0471"(MINT)
Interaction identifier(s) in the corresponding source databaseintact:EBI-8067988
mint:MINT-7894271
imex:IM-15593-2
Confidence scoreintact-miscore:0.54
Complex expansion-
Biological role AUnspecified role
Biological role BUnspecified role
Experimental role ABait
Experimental role BPrey
Interactor type AProtein
Interactor type BProtein
Annotations for the interactionfigure legend:f3a
comment:homomint
comment:mint
causality statement:Q9HCE7-2 increases degradation at protein level of Q9H160
causality statement:Q9HCE7-2 is required for ubiquitination of Q9H160
dataset:IBD - Inflammatory bowel disease
full coverage:Only protein-protein interactions
curation depth:imex curation
NCBI Taxonomy identifier for the host organismtaxid:-1(in vitro)
taxid:-1(In vitro)
Parameters of the interaction-
Creation date2010/05/17
Update date2014/11/18
negative Boolean valuefalse
Feature(s) for interactor Aglutathione s tranferase tag:?-?(MINT-7894274)
Feature(s) for interactor Bhis tag:?-?(MINT-7894278)
Stoichiometry for interactor A-
Stoichiometry for interactor B-
Participant identification method for interactor AAnti tag western blot
Participant identification method for interactor BAnti tag western blot